BCAS3

BCAS3 microtubule associated cell migration factor

Summary

Enables several functions, including acetyltransferase activator activity; beta-tubulin binding activity; and histone acetyltransferase binding activity. Involved in cellular response to estrogen stimulus; positive regulation of catalytic activity; and positive regulation of transcription by RNA polymerase II. Located in euchromatin; nucleus; and phagophore assembly site. Implicated in Hengel-Maroofian-Schols syndrome. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants131 total

rsidPosition (GRCh37)AllelesClassClinVar
rs214378284117:58,756,891C/T—pathogenic
rs104126939617:58,761,356A/G—uncertain significance
rs75575411517:58,767,086A/G—uncertain significance
rs254451582917:58,767,096T/C—uncertain significance
rs18105944217:58,782,696A/Gintron variant—
rs264310317:58,786,625A/Gmissense variant—
rs214426066017:58,824,574C/T—likely pathogenic
rs76063019317:58,824,595C/T—uncertain significance
rs76410928817:58,824,596A/C—uncertain significance
rs254466325817:58,824,623T/A—likely pathogenic
rs13974058517:58,839,165T/Cintron variant—
rs2846234217:58,852,269T/Cintron variant—
rs18796133417:58,857,123C/Tintron variant—
rs140736544917:58,885,367G/C—uncertain significance
rs990380117:58,915,261G/Cintron variant—
rs990722917:58,917,399T/Cintron variant—
rs991036517:58,930,419A/Gdownstream gene variant—
rs807312017:58,931,385T/Adownstream gene variant—
rs76106919317:58,946,036C/A—likely pathogenic
rs37775237317:58,946,043C/T—uncertain significance
rs76234960617:58,952,030G/T—uncertain significance
rs13876054617:58,959,336A/T——
rs930342917:58,965,400C/A——
rs722443817:58,966,538T/Cintron variant—
rs75972081017:58,967,062A/G—uncertain significance
rs19985057617:58,967,091A/G—likely benign
rs75826806717:58,967,106C/T—uncertain significance
rs214500003617:58,967,120T/G—pathogenic
rs7977128617:58,971,731A/Tintron variant—
rs20155665617:58,980,003G/A—uncertain significance
rs989780317:58,981,156G/T——
rs118781368617:58,987,960G/A—uncertain significance
rs75501309017:58,987,974G/A—likely benign
rs144654536717:58,987,975A/C—uncertain significance
rs20104785517:58,987,981C/T—uncertain significance
rs77337794717:58,987,990G/A—uncertain significance
rs20085082017:58,988,001C/T—uncertain significance
rs14020727717:58,988,043G/A—uncertain significance
rs721422717:58,991,025C/Tintron variant—
rs19975633217:59,001,785T/G—uncertain significance
rs254504838417:59,001,819G/C—uncertain significance
rs74805647217:59,001,820C/T—uncertain significance
rs99527404117:59,001,855A/T—uncertain significance
rs77272350317:59,001,856C/T—uncertain significance
rs650400917:59,003,383G/Aintron variant—
rs721279817:59,013,488T/A——
rs5704300917:59,023,998C/Tintron variant—
rs20051592217:59,024,649G/T—uncertain significance
rs198807817:59,030,299C/Tintron variant—
rs991614517:59,031,608A/Gintron variant—
rs720920417:59,046,936A/T——
rs55803041017:59,067,459G/A—uncertain significance
rs77964565317:59,067,471G/T—uncertain significance
rs20119794417:59,067,480G/A—uncertain significance
rs3605528517:59,067,526G/A—benign
rs214543291717:59,067,567C/G—pathogenic
rs965285817:59,087,808G/Aintron variant—
rs75580849417:59,093,142A/G—uncertain significance
rs134215565317:59,093,151A/G—uncertain significance
rs75759951717:59,093,172G/A—uncertain significance
rs101330366017:59,093,195A/G—uncertain significance
rs131197543017:59,093,197G/A—uncertain significance
rs77087212017:59,093,231A/G—uncertain significance
rs77630412717:59,104,262A/G—uncertain significance
rs77971558317:59,112,043C/T—uncertain significance
rs75485727617:59,112,044C/T—pathogenic
rs77281326517:59,112,073G/A—pathogenic
rs13996189417:59,112,109A/G—uncertain significance
rs86690642817:59,112,130G/T—uncertain significance
rs19975687117:59,115,285A/G—uncertain significance
rs76927954117:59,115,367C/G—uncertain significance
rs95622533217:59,115,382T/C—uncertain significance
rs76993954417:59,115,393C/T—pathogenic
rs77324083917:59,115,394G/T—uncertain significance
rs76664804417:59,115,411G/A—uncertain significance
rs250924605017:59,118,218A/G—uncertain significance
rs20106135317:59,152,328G/A—uncertain significance
rs250938937217:59,155,718C/A—uncertain significance
rs78169504817:59,155,728G/A—uncertain significance
rs214348781617:59,155,745C/T—likely pathogenic
rs250938956217:59,155,754T/A—uncertain significance
rs37270085517:59,155,787G/A—uncertain significance
rs137079820417:59,155,824G/A—uncertain significance
rs74676576417:59,155,827C/T—uncertain significance
rs75926489317:59,155,836C/T—uncertain significance
rs250940776817:59,161,886G/C—uncertain significance
rs75057679117:59,161,920C/T—uncertain significance
rs214353880217:59,161,925G/C—likely pathogenic
rs147609817:59,237,013A/G——
rs7283256317:59,238,157C/Tintron variant—
rs19138012117:59,238,252C/Tintron variant—
rs237881617:59,239,149T/Aintron variant—
rs1186844117:59,239,221A/Gintron variant—
rs1107941817:59,239,754T/C——
rs807389417:59,241,155T/G——
rs807436317:59,241,469T/Cintron variant—
rs807361117:59,241,768A/G——
rs808012317:59,242,914T/A——
rs1107941917:59,247,327T/A——
rs464025017:59,250,013A/G——

Showing 100 of 131 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.