Trait
SNPs associated with Nephrolithiasis
171 genetic variants across 46 genes have been associated with Nephrolithiasis in published research. Key genes include ABCC6, ABCG2, ALPL.
Associated variants171 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs77924615 | — | GWAS association (p=2.0e-94) | Major Consortium Study |
| rs56235845 | RGS14 | GWAS association (p=8.0e-73) | Major Consortium Study |
| rs4074995 | RGS14 | GWAS association (p=2.0e-57) | Major Consortium Study |
| rs2231142 | ABCG2 | GWAS association (p=5.0e-51) | Major Consortium Study |
| rs219772 | CLDN14 | GWAS association (p=3.0e-45) | Major Consortium Study |
| rs6127099 | — | GWAS association (p=4.0e-39) | Major Consortium Study |
| rs2299905 | AQP1 | GWAS association (p=6.0e-30) | Major Consortium Study |
| rs9897621 | KANSL1 | GWAS association (p=7.0e-30) | Major Consortium Study |
| rs9895661 | BCAS3 | GWAS association (p=3.0e-29) | Major Consortium Study |
| rs1772719 | ALPL | GWAS association (p=1.0e-26) | Major Consortium Study |
| rs9612214 | — | GWAS association (p=2.0e-24) | Major Consortium Study |
| rs142212375 | — | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs2241358 | GIPC1 | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs2206271 | TFAP2B | GWAS association (p=7.0e-20) | Major Consortium Study |
| rs838718 | — | GWAS association (p=3.0e-19) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=5.0e-18) | Major Consortium Study |
| rs41278174 | ABCC6 | GWAS association (p=7.0e-18) | Major Consortium Study |
| rs7583875 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs2238691 | GIPR | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs4252512 | — | GWAS association (p=5.0e-17) | Major Consortium Study |
| rs6767061 | CASR | GWAS association (p=9.0e-17) | Major Consortium Study |
| rs12947281 | — | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs13147491 | — | GWAS association (p=3.0e-16) | Major Consortium Study |
| rs1347548 | STC1 | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs12600751 | FBXL20 | GWAS association (p=8.0e-16) | Major Consortium Study |
| rs4782302 | — | GWAS association (p=2.0e-14) | Major Consortium Study |
| rs10223666 | POLR1C | GWAS association (p=7.0e-14) | Major Consortium Study |
| rs4930319 | OVOL1 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs11879227 | SNRPD2 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs61104187 | HLA-DRB6 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs9463653 | — | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs78369364 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs7533348 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs10196396 | — | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs10265221 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs13358767 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs10051765 | — | GWAS association (p=4.0e-47) | Large GWAS |
| rs2776288 | — | GWAS association (p=1.0e-40) | Large GWAS |
| rs1936824 | — | GWAS association (p=5.0e-32) | Large GWAS |
| rs670676 | DGKH | GWAS association (p=2.0e-31) | Large GWAS |
| rs35194449 | — | GWAS association (p=3.0e-29) | Large GWAS |
| rs1037271 | — | GWAS association (p=1.0e-24) | Large GWAS |
| rs838717 | — | GWAS association (p=6.0e-23) | Large GWAS |
| rs12626330 | — | GWAS association (p=7.0e-21) | Large GWAS |
| rs4142110 | DGKH | GWAS association (p=3.0e-20) | Large GWAS |
| rs13054904 | — | GWAS association (p=3.0e-20) | Large GWAS |
| rs3760702 | GIPC1 | GWAS association (p=3.0e-19) | Large GWAS |
| rs6556316 | SLC34A1 | GWAS association (p=3.0e-19) | Large GWAS |
| rs3788338 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs77362499 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs56008432 | LINC02003 | GWAS association (p=3.0e-17) | Large GWAS |
| rs4148155 | ABCG2 | GWAS association (p=4.0e-17) | Large GWAS |
| rs1404278 | — | GWAS association (p=8.0e-17) | Large GWAS |
| rs6694088 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs71606723 | — | GWAS association (p=3.0e-15) | Large GWAS |
| rs1010269 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs200495345 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs9533022 | — | GWAS association (p=4.0e-15) | Large GWAS |
| rs11077601 | LINC02003 | GWAS association (p=7.0e-15) | Large GWAS |
| rs42085 | — | GWAS association (p=8.0e-15) | Large GWAS |
| rs2079742 | BCAS3 | GWAS association (p=1.0e-14) | Large GWAS |
| rs11723275 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs6857337 | UGT8 | GWAS association (p=3.0e-14) | Large GWAS |
| rs780093 | GCKR | GWAS association (p=1.0e-13) | Large GWAS |
| rs199565725 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs3134962 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs2459380 | WDR72 | GWAS association (p=9.0e-13) | Large GWAS |
| rs7277076 | — | GWAS association (p=9.0e-13) | Large GWAS |
| rs729761 | POLR1C | GWAS association (p=1.0e-12) | Large GWAS |
| rs9516602 | CLDN10 | GWAS association (p=2.0e-12) | Large GWAS |
| rs2202126 | CASR | GWAS association (p=3.0e-12) | Large GWAS |
| rs62405419 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs219780 | CLDN14 | GWAS association (p=4.0e-12) | Large GWAS |
| rs55637647 | ZFPM1 | GWAS association (p=4.0e-12) | Large GWAS |
| rs77759957 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs35747824 | PDILT | GWAS association (p=8.0e-12) | Large GWAS |
| rs6586063 | SHLD2 | GWAS association (p=1.0e-11) | Large GWAS |
| rs7790498 | HIBADH | GWAS association (p=1.0e-11) | Large GWAS |
| rs12921916 | — | GWAS association (p=1.0e-11) | Large GWAS |
| rs1182959 | DGKH | GWAS association (p=2.0e-11) | Large GWAS |
| rs10917002 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs113831804 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs13003198 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs56094641 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs1170174 | DGKH | GWAS association (p=5.0e-11) | Large GWAS |
| rs12654812 | RGS14 | GWAS association (p=6.0e-11) | Large GWAS |
| rs1256332 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs578595 | WDR72 | GWAS association (p=6.0e-11) | Large GWAS |
| rs10807202 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs57719175 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs7974476 | — | GWAS association (p=8.0e-11) | Large GWAS |
| rs12539707 | HIBADH | GWAS association (p=1.0e-10) | Large GWAS |
| rs34783010 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs34172859 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs638333 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs239208 | ASCC3 | GWAS association (p=4.0e-10) | Large GWAS |
| rs4529910 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs9472142 | POLR1C | GWAS association (p=4.0e-10) | Large GWAS |
| rs77648599 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs138789058 | — | GWAS association (p=5.0e-10) | Large GWAS |
Showing the top 100 of 171 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.