rs34783010

GWAS Catalog Trait Associations (18)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

serum urea amount

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.05
p 1.0e-59
N 355,637
Major Consortium StudyLarge GWAS
multi-ancestry

obesity

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 0.06
p 7.0e-24
N 585,585
Major Consortium StudyLarge GWAS
multi-ancestry

sodium measurement

Allele G
OR 0.01
p 8.0e-18
N 446,237
Large GWAS
multi-ancestry
Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.02
p 6.0e-13
N 345,171
Major Consortium StudyLarge GWAS
multi-ancestry

taste liking measurement

Allele T
OR 0.04
p 3.0e-16
N 159,246
Large GWAS
European

pulse pressure measurement

Allele T
OR 0.17
p 2.0e-15
N 757,601
Large GWAS
European
Yang ML et al. Sex-specific genetic architecture of blood pressure. Nature Medicine 30(3):818-828 (2024)
Allele T
OR 0.02
p 1.0e-9
N 349,328
Large GWAS
multi-ancestry

serum creatinine amount

Allele T
OR 0.02
p 3.0e-15
N 394,642
Large GWAS
European
Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.02
p 7.0e-10
N 355,731
Major Consortium StudyLarge GWAS
multi-ancestry

urinary potassium to creatinine ratio

Allele T
OR 0.03
p 1.0e-13
N 218,435
Large GWAS
European

low density lipoprotein cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.02
p 6.0e-11
N 355,197
Major Consortium StudyLarge GWAS
multi-ancestry

apolipoprotein B measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.02
p 1.0e-10
N 354,097
Major Consortium StudyLarge GWAS
multi-ancestry

nephrolithiasis

Allele T
OR 0.94
p 2.0e-10
N 975,370
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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