rs3760702
This is a downstream gene variant variant in the GIPC1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
nephrolithiasis
Cao X et al. “Trans-ancestry GWAS identifies 59 loci and improves risk prediction and fine-mapping for kidney stone disease.” Nature Communications 16(1):3473 (2025)
Allele A
OR 1.09
p 3.0e-19
N 975,370
Large GWAS
multi-ancestry
Lovegrove CE et al. “Central Adiposity Increases Risk of Kidney Stone Disease through Effects on Serum Calcium Concentrations.” Journal of the American Society of Nephrology : Jasn 34(12):1991-2011 (2023)
Allele A
OR 1.07
p 8.0e-9
N 739,048
Large GWAS
European
Howles SA et al. “Genetic variants of calcium and vitamin D metabolism in kidney stone disease.” Nature Communications 10(1):5175 (2019)
Allele A
OR 1.09
p 2.0e-9
N 429,501
Large GWAS
multi-ancestry
About GIPC1
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]
View all GIPC1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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