rs35194449
This is a intergenic variant variant.
▶GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
calcium measurement
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.05
p 6.0e-40
N 355,606
Major Consortium StudyLarge GWAS
multi-ancestry
nephrolithiasis
Cao X et al. “Trans-ancestry GWAS identifies 59 loci and improves risk prediction and fine-mapping for kidney stone disease.” Nature Communications 16(1):3473 (2025)
Allele T
OR 0.88
p 3.0e-29
N 975,370
Large GWAS
multi-ancestry
serum creatinine amount
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.03
p 4.0e-18
N 600,139
Major Consortium StudyLarge GWAS
multi-ancestry
glomerular filtration rate
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.03
p 1.0e-17
N 571,230
Major Consortium StudyLarge GWAS
multi-ancestry
blood parathyroid hormone amount
Robinson-Cohen C et al. “Genetic Variants Associated with Circulating Parathyroid Hormone.” Journal of the American Society of Nephrology : Jasn 28(5):1553-1565 (2017)
Allele T
OR 4.00
p 2.0e-10
N 22,653
Large GWAS
European
bone tissue density
Qian 钱雨 Y et al. “Genome-wide Association Studies of over 30,000 Samples with Bone Mineral Density at Multiple Skeletal Sites and Its Clinical Relevance.” Genomics, Proteomics & Bioinformatics 23(5) (2025)
Allele T
OR 0.07
p 3.0e-10
N 31,873
Large GWAS
European
urolithiasis
Ishigaki K et al. “Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.” Nature Genetics 52(7):669-679 (2020)
Allele T
OR 0.84
p 1.0e-8
N 212,453
Large GWAS
East Asian
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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