rs6127099
▶GWAS Catalog Trait Associations (19)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (19)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
calcium measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.05
p 8.0e-90
N 394,642
Large GWAS
European
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 0.05
p 1.0e-45
N 250,885
Major Consortium StudyLarge GWAS
European
blood parathyroid hormone amount
Robinson-Cohen C et al. “Genetic Variants Associated with Circulating Parathyroid Hormone.” Journal of the American Society of Nephrology : Jasn 28(5):1553-1565 (2017)
Allele T
OR 0.07
p 2.0e-72
N 22,653
Large GWAS
European
vitamin D level
Manousaki D et al. “Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci.” American Journal of Human Genetics 106(3):327-337 (2020)
Allele T
OR 0.04
p 9.0e-62
N 443,734
Large GWAS
European
Manousaki D et al. “Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.” American Journal of Human Genetics 101(2):227-238 (2017)
Allele T
OR 0.06
p 2.0e-17
N 42,274
Large GWAS
European
bladder calculus
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.12
p 5.0e-44
N 433,456
Major Consortium StudyLarge GWAS
European
fibroblast growth factor 23 level
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.08
p 1.0e-42
N 47,745
Large GWAS
European
nephrolithiasis
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.12
p 4.0e-39
N 435,154
Major Consortium StudyLarge GWAS
European
Lovegrove CE et al. “Central Adiposity Increases Risk of Kidney Stone Disease through Effects on Serum Calcium Concentrations.” Journal of the American Society of Nephrology : Jasn 34(12):1991-2011 (2023)
Allele A
OR 1.15
p 2.0e-29
N 739,048
Large GWAS
European
intact parathyroid hormone measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.08
p 9.0e-35
N 47,745
Large GWAS
European
serum urea amount
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.02
p 3.0e-27
N 394,642
Large GWAS
European
serum creatinine amount, glomerular filtration rate
Gorski M et al. “1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.” Scientific Reports 7:45040 (2017)
Allele A
OR 0.01
p 3.0e-17
N 110,517
Meta-analysisLarge GWAS
European
urate measurement
Major TJ et al. “A genome-wide association analysis reveals new pathogenic pathways in gout.” Nature Genetics 56(11):2392-2406 (2024)
Allele A
OR 0.02
p 1.0e-14
N 630,117
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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