SLC39A7

solute carrier family 39 member 7

Summary

The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Known Variants162 total

rsidPosition (GRCh37)AllelesClassClinVar
rs17745178176:33,169,027C/T—uncertain significance
rs25357712816:33,169,049C/A—uncertain significance
rs3739726346:33,169,055G/C—likely benign
rs21506809536:33,169,065C/A—uncertain significance
rs3678529036:33,169,072C/A—uncertain significance
rs9566570496:33,169,075G/A—likely pathogenic
rs25357717506:33,169,092C/T—likely benign
rs3705280396:33,169,095G/A—uncertain significance
rs13913523626:33,169,106C/T—likely benign
rs7594271226:33,169,111G/C—conflicting classifications of pathogenicity
rs3747087116:33,169,121C/T—likely benign
rs7771294846:33,169,124G/T—likely benign
rs7623389406:33,169,170T/C—uncertain significance
rs7638651796:33,169,174A/T—uncertain significance
rs769296556:33,169,182T/C—likely benign
rs29752976:33,169,193C/A—benign
rs5597707426:33,169,196C/G—uncertain significance
rs2017506936:33,169,221A/G—uncertain significance
rs12269543506:33,169,226C/G—uncertain significance
rs12108133586:33,169,233A/T—uncertain significance
rs7769332196:33,169,251C/T—uncertain significance
rs17745551806:33,169,253C/T—likely benign
rs342111886:33,169,281G/A—likely benign
rs3755571496:33,169,291A/G—uncertain significance
rs21506820616:33,169,353G/A—uncertain significance
rs17745687496:33,169,368G/A—uncertain significance
rs356907126:33,169,392G/C—likely benign
rs7585140726:33,169,394C/T—uncertain significance
rs25357758236:33,169,398A/C—uncertain significance
rs3746961246:33,169,422C/A—uncertain significance
rs2016457406:33,169,432A/T—uncertain significance
rs3734060746:33,169,445G/A—likely benign
rs10473172696:33,169,527G/A—likely benign
rs15834324756:33,169,531G/A—uncertain significance
rs7660249876:33,169,536A/G—likely benign
rs5726106146:33,169,538T/C—uncertain significance
rs1378731616:33,169,571T/G—uncertain significance
rs115388106:33,169,581C/T—benign
rs25357778606:33,169,593C/A—uncertain significance
rs11856693266:33,169,595C/G—uncertain significance
rs25357780386:33,169,598C/G—uncertain significance
rs7477150296:33,169,600C/T—uncertain significance
rs3711009216:33,169,614A/C—likely benign
rs12004300326:33,169,641C/T—likely benign
rs17746023706:33,169,653G/A—likely benign
rs7652094736:33,169,674C/G—likely benign
rs5638664646:33,169,678C/G—likely pathogenic
rs21506830916:33,169,679C/T—uncertain significance
rs5330114406:33,169,681C/T—uncertain significance
rs3735093036:33,169,688T/A—uncertain significance
rs9410343396:33,169,700C/G—likely benign
rs25357793456:33,169,702C/A—likely benign
rs17746075146:33,169,706C/T—likely benign
rs2016206396:33,169,709C/T—likely benign
rs13056373326:33,169,710T/G—likely benign
rs11566070416:33,169,830T/C—likely benign
rs21506835926:33,169,831T/A—likely benign
rs13444280296:33,169,833T/C—likely benign
rs412667016:33,169,839A/C—benign
rs7553962976:33,169,868T/G—likely benign
rs21506837746:33,169,874G/A—likely benign
rs25357814536:33,169,877A/G—likely benign
rs3753608236:33,169,880C/T—likely benign
rs1459449696:33,169,881G/A—likely benign
rs12125369006:33,169,885A/G—uncertain significance
rs15473876:33,169,895C/G—benign
rs7669547426:33,169,915C/G—likely benign
rs1177535596:33,169,920G/A—likely benign
rs3761116386:33,169,921G/A—likely benign
rs7455487056:33,170,028C/T—likely benign
rs9660071866:33,170,037C/A—uncertain significance
rs25357836086:33,170,047C/T—likely benign
rs7684893436:33,170,050C/T—likely benign
rs2007530576:33,170,052T/C—uncertain significance
rs11700383776:33,170,055T/C—pathogenic
rs21506844506:33,170,058C/T—uncertain significance
rs25357839716:33,170,068G/A—likely benign
rs17746554646:33,170,083A/C—likely benign
rs25357843076:33,170,087G/C—uncertain significance
rs2019870886:33,170,102G/A—uncertain significance
rs1131981036:33,170,149C/T—likely benign
rs7797446316:33,170,152A/G—likely benign
rs17746652956:33,170,153C/T—uncertain significance
rs7537661856:33,170,161C/T—likely benign
rs7720917106:33,170,169G/T—uncertain significance
rs7460037566:33,170,178G/A—uncertain significance
rs348364016:33,170,194T/C—benign
rs7632117336:33,170,221C/G—likely benign
rs7535087716:33,170,326T/C—likely benign
rs1134528036:33,170,327C/A—likely benign
rs9432351036:33,170,339C/T—conflicting classifications of pathogenicity
rs7784017426:33,170,340G/A—uncertain significance
rs7480289406:33,170,341T/C—likely benign
rs13453242526:33,170,344T/C—likely benign
rs21506854176:33,170,348A/G—uncertain significance
rs7779254686:33,170,362C/T—likely benign
rs7802342066:33,170,381G/A—uncertain significance
rs2001002796:33,170,384A/C—benign
rs11829679236:33,170,389A/G—likely benign
rs21506856026:33,170,392G/A—likely benign

Showing 100 of 162 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.