rs35690712

This variant is located in the SLC39A7 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

collagen alpha-2(XI) chain measurement

Sun BB et al. “Genomic atlas of the human plasma proteome.” Nature 558(7708):73-79 (2018)

Allele C

OR 0.69

p 6.0e-22

N 3,301

Large GWAS

European

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ClinVar annotation

Likely Benign★★★☆

3 submitters2 publications

not provided; not specified

View on ClinVar →

About SLC39A7

The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

View all SLC39A7 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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