STMN3
stathmin 3
Summary
This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Known Variants17 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs909333 | 20:62,270,637 | T/A | — | — |
| rs560157163 | 20:62,272,165 | C/T | — | — |
| rs6423444 | 20:62,272,411 | G/A | regulatory region variant | — |
| rs3865523 | 20:62,272,583 | G/A | — | — |
| rs1365314943 | 20:62,272,704 | T/C | — | uncertain significance |
| rs749257260 | 20:62,273,477 | T/G | — | uncertain significance |
| rs1259742200 | 20:62,273,487 | C/A | — | uncertain significance |
| rs1187704824 | 20:62,273,492 | A/C | — | uncertain significance |
| rs2089787390 | 20:62,275,151 | C/A | — | uncertain significance |
| rs201304064 | 20:62,275,218 | G/A | — | uncertain significance |
| rs2516966309 | 20:62,275,225 | T/C | — | uncertain significance |
| rs2516966336 | 20:62,275,248 | C/T | — | uncertain significance |
| rs749713904 | 20:62,275,624 | G/A | — | uncertain significance |
| rs62207015 | 20:62,279,040 | G/A | intron variant | — |
| rs6010990 | 20:62,281,476 | T/C | intron variant | — |
| rs112087793 | 20:62,284,170 | C/T | regulatory region variant | — |
| rs1015465646 | 20:62,284,684 | A/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.