Trait
SNPs associated with Idiopathic pulmonary fibrosis
66 genetic variants across 31 genes have been associated with Idiopathic pulmonary fibrosis in published research. Key genes include AKAP13, ANK1, CDYL2.
Associated variants66 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs35705950 | MUC5B | Higher risk of idiopathic pulmonary fibrosis | Meta-analysis |
| rs2076295 | DSP | GWAS association (p=2.0e-48) | Meta-analysis |
| rs116483731 | — | GWAS association (p=2.0e-20) | Meta-analysis |
| rs776981958 | TERT | GWAS association (p=3.0e-20) | Meta-analysis |
| rs35379604 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs148583745 | GMEB2 | GWAS association (p=7.0e-10) | Meta-analysis |
| rs708686 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs7549256 | — | GWAS association (p=3.0e-09) | Meta-analysis |
| rs539683219 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs9266669 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs967235139 | TACC2 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs34288126 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs2736100 | TERT | Higher idiopathic pulmonary fibrosis risk | Meta-analysis |
| rs76537958 | LOC107986324 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs9380529 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs4130548 | — | GWAS association (p=5.0e-08) | Meta-analysis |
| rs191874689 | EFNA5 | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs74801462 | IL23R | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs531386441 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs545858325 | AKAP13 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs540045900 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs190103938 | CDYL2 | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs192570325 | ANK1 | GWAS association (p=7.0e-12) | Major Consortium Study |
| rs377375108 | CNTNAP2 | GWAS association (p=8.0e-12) | Major Consortium Study |
| rs573220231 | LOC105370955 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs535550249 | FADS6 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs182978445 | — | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs554880413 | NRXN3 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs554085697 | CEP128 | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs148503153 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs544465873 | DLG2 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs575303072 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs577594273 | GRIK4 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs7725218 | TERT | GWAS association (p=5.0e-32) | Large GWAS |
| rs2897075 | ZKSCAN1 | GWAS association (p=2.0e-21) | Large GWAS |
| rs2077551 | KANSL1 | GWAS association (p=2.0e-20) | Large GWAS |
| rs12699415 | — | GWAS association (p=9.0e-20) | Large GWAS |
| rs2304645 | — | GWAS association (p=9.0e-20) | Large GWAS |
| rs12537430 | MAD1L1 | GWAS association (p=4.0e-18) | Large GWAS |
| rs9860874 | — | GWAS association (p=6.0e-18) | Large GWAS |
| rs2609259 | FAM13A | GWAS association (p=6.0e-17) | Large GWAS |
| rs12610495 | DPP9 | GWAS association (p=3.0e-16) | Large GWAS |
| rs59424629 | — | GWAS association (p=7.0e-16) | Large GWAS |
| rs78238620 | KIF15 | GWAS association (p=4.0e-14) | Large GWAS |
| rs9577395 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs2013701 | FAM13A | GWAS association (p=3.0e-13) | Large GWAS |
| rs2292181 | KIF15 | GWAS association (p=4.0e-13) | Large GWAS |
| rs12696304 | — | GWAS association (p=7.0e-13) | Large GWAS |
| rs12912339 | KNL1 | GWAS association (p=7.0e-13) | Large GWAS |
| rs5743894 | TOLLIP | GWAS association (p=1.0e-12) | Large GWAS |
| rs74614704 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs28513081 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs5743890 | TOLLIP | GWAS association (p=3.0e-11) | Large GWAS |
| rs10808505 | DEPTOR | GWAS association (p=6.0e-11) | Large GWAS |
| rs62023891 | AKAP13 | GWAS association (p=1.0e-10) | Large GWAS |
| rs41308092 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs7100920 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs62025270 | LINC02883 | GWAS association (p=1.0e-09) | Large GWAS |
| rs11073517 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs73606754 | TTYH1 | GWAS association (p=3.0e-09) | Large GWAS |
| rs4233306 | — | GWAS association (p=3.0e-09) | Large GWAS |
| rs17690703 | MAPT-AS1 | GWAS association (p=6.0e-09) | Large GWAS |
| rs112087793 | STMN3 | GWAS association (p=1.0e-08) | Large GWAS |
| rs1214759 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs79684490 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs11788059 | — | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.