rs73606754
This variant is located in the TTYH1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
idiopathic pulmonary fibrosis
Allen RJ et al. “Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.” The Lancet. Respiratory Medicine 5(11):869-880 (2017)
Allele C
OR 1.54
p 3.0e-9
N 3,968
Large GWAS
European
About TTYH1
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jan 2011]
View all TTYH1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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