GMEB2
glucocorticoid modulatory element binding protein 2
Summary
This gene is a member of KDWK gene family. The product of this gene associates with GMEB1 protein, and the complex is essential for parvovirus DNA replication. Study of rat homolog implicates the role of this gene in modulation of transactivation by the glucocorticoid receptor bound to glucocorticoid response elements. This gene appears to use multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
Known Variants33 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs973542159 | 20:62,221,453 | C/T | — | uncertain significance |
| rs145516314 | 20:62,221,491 | G/A | — | uncertain significance |
| rs1367482279 | 20:62,221,572 | T/C | — | uncertain significance |
| rs898807447 | 20:62,221,683 | G/A | — | uncertain significance |
| rs748067783 | 20:62,221,684 | C/T | — | uncertain significance |
| rs2516888953 | 20:62,221,696 | T/G | — | uncertain significance |
| rs138097488 | 20:62,221,738 | C/G | — | uncertain significance |
| rs749311215 | 20:62,221,779 | G/A | — | uncertain significance |
| rs199786039 | 20:62,221,810 | C/T | — | uncertain significance |
| rs374807605 | 20:62,221,867 | C/T | — | uncertain significance |
| rs776714259 | 20:62,221,922 | C/T | — | likely benign |
| rs3787112 | 20:62,222,411 | G/A | intron variant | — |
| rs889470145 | 20:62,223,399 | C/G | — | uncertain significance |
| rs2516893809 | 20:62,223,413 | A/G | — | uncertain significance |
| rs765871536 | 20:62,223,429 | T/C | — | uncertain significance |
| rs2516893966 | 20:62,223,470 | T/C | — | uncertain significance |
| rs769306023 | 20:62,223,888 | C/T | — | uncertain significance |
| rs1569047768 | 20:62,223,932 | C/T | — | uncertain significance |
| rs368815293 | 20:62,223,947 | C/G | — | uncertain significance |
| rs2516895350 | 20:62,223,948 | T/A | — | uncertain significance |
| rs2516895360 | 20:62,223,949 | C/G | — | uncertain significance |
| rs779896394 | 20:62,224,376 | C/T | — | likely benign |
| rs1302945719 | 20:62,224,430 | C/A | — | uncertain significance |
| rs1202096555 | 20:62,227,026 | G/A | — | uncertain significance |
| rs2516902426 | 20:62,227,065 | T/C | — | uncertain significance |
| rs545692804 | 20:62,229,210 | C/T | — | uncertain significance |
| rs369041738 | 20:62,234,406 | A/G | — | uncertain significance |
| rs148481039 | 20:62,235,990 | G/C | intron variant | — |
| rs777285269 | 20:62,236,138 | C/A | — | uncertain significance |
| rs1412529326 | 20:62,236,178 | T/A | — | uncertain significance |
| rs77209743 | 20:62,239,772 | G/C | — | — |
| rs1421300921 | 20:62,250,687 | C/T | — | uncertain significance |
| rs148583745 | 20:62,254,696 | A/G | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.