rs10808505
This is a intron variant variant in the DEPTOR gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
idiopathic pulmonary fibrosis
Allen RJ et al. “Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis.” Thorax 77(8):829-833 (2022)
Allele T
OR 1.20
p 6.0e-11
N 24,589
Large GWAS
European
About DEPTOR
Enables phosphatidic acid binding activity and protein serine/threonine kinase inhibitor activity. Involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Is active in lysosomal membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all DEPTOR variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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