TACR3

tachykinin receptor 3

Summary

This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008]

Known Variants115 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs112175823	4:104,510,569	A/G	—	likely benign
rs886058970	4:104,510,637	C/G	—	uncertain significance
rs145839786	4:104,510,696	C/T	—	uncertain significance
rs200193311	4:104,510,701	C/T	—	uncertain significance
rs201125726	4:104,510,714	T/C	—	uncertain significance
rs1723845345	4:104,510,745	A/C	—	uncertain significance
rs199959009	4:104,510,752	A/G	—	uncertain significance
rs2765	4:104,510,766	G/A	—	benign
rs564772018	4:104,510,844	A/G	—	likely benign
rs1723849531	4:104,510,864	T/C	—	uncertain significance
rs17033889	4:104,510,892	C/A	—	uncertain significance
rs76121575	4:104,510,893	G/A	—	likely benign
rs146482011	4:104,510,916	G/A	—	conflicting classifications of pathogenicity
rs886058972	4:104,510,926	A/G	—	uncertain significance
rs138661164	4:104,510,947	C/T	—	conflicting classifications of pathogenicity
rs200736098	4:104,510,948	G/A	—	uncertain significance
rs143073792	4:104,510,991	T/A	—	conflicting classifications of pathogenicity
rs151158699	4:104,511,003	C/T	—	uncertain significance
rs886058973	4:104,511,007	T/A	—	uncertain significance
rs201828791	4:104,511,012	T/C	—	conflicting classifications of pathogenicity
rs201120800	4:104,511,031	G/A	—	uncertain significance
rs886058974	4:104,511,049	C/T	—	uncertain significance
rs201473070	4:104,511,070	G/A	—	likely benign
rs2476194907	4:104,511,073	C/T	—	likely benign
rs1353918699	4:104,511,078	G/A	—	uncertain significance
rs1458405524	4:104,511,119	C/A	—	uncertain significance
rs199740086	4:104,511,147	G/A	—	likely pathogenic
rs150702614	4:104,511,357	G/A	—	likely benign
rs184589436	4:104,511,365	G/C	—	likely benign
rs6847994	4:104,512,451	T/C	—	benign
rs73835380	4:104,512,488	G/T	—	benign
rs6822961	4:104,512,628	G/A	—	benign
rs2110283162	4:104,512,631	G/T	—	likely benign
rs139363165	4:104,512,667	G/A	—	likely benign
rs121918125	4:104,512,672	G/A	missense variant	pathogenic
rs2476197212	4:104,512,713	A/G	—	uncertain significance
rs369387303	4:104,512,765	T/C	—	uncertain significance
rs765648107	4:104,512,775	G/A	—	likely benign
rs1723899410	4:104,512,799	G/C	—	uncertain significance
rs34550211	4:104,512,808	T/G	—	likely benign
rs201088165	4:104,512,811	C/T	—	uncertain significance
rs886058975	4:104,512,812	A/G	—	uncertain significance
rs376656496	4:104,512,837	C/T	—	uncertain significance
rs74827081	4:104,556,732	G/C	intron variant	—
rs9968304	4:104,558,149	C/T	intron variant	—
rs7679478	4:104,558,727	T/C	—	—
rs1384401	4:104,565,078	G/A	intron variant	—
rs3796964	4:104,568,816	C/A	—	—
rs78047097	4:104,577,177	C/T	—	likely benign
rs143547106	4:104,577,274	A/G	—	likely benign
rs2476286785	4:104,577,359	T/C	—	uncertain significance
rs35085919	4:104,577,366	T/C	—	benign
rs2276973	4:104,577,382	T/C	—	likely benign
rs144292455	4:104,577,415	C/T	stop gained	pathogenic
rs768209062	4:104,577,459	C/T	—	likely benign
rs1057524840	4:104,577,464	G/A	—	uncertain significance
rs397515483	4:104,577,473	A/G	missense variant	pathogenic
rs148732080	4:104,577,494	T/C	—	uncertain significance
rs1374236686	4:104,577,496	T/C	—	uncertain significance
rs780986051	4:104,579,115	T/G	—	likely benign
rs760022956	4:104,579,371	C/T	—	pathogenic
rs200991185	4:104,579,372	G/A	—	uncertain significance
rs1464819488	4:104,579,379	G/A	—	uncertain significance
rs886058976	4:104,579,406	C/T	—	uncertain significance
rs764659822	4:104,579,417	G/A	missense variant	pathogenic
rs1195516345	4:104,579,421	G/A	—	uncertain significance
rs757975317	4:104,579,422	G/T	—	likely benign
rs201587477	4:104,579,429	A/G	—	uncertain significance
rs727505375	4:104,579,486	C/T	stop gained	pathogenic
rs748064766	4:104,579,498	A/G	—	uncertain significance
rs199915379	4:104,579,503	A/T	—	likely benign
rs2476289080	4:104,579,515	T/A	—	likely benign
rs62340657	4:104,579,530	G/A	—	conflicting classifications of pathogenicity
rs10516505	4:104,579,674	G/T	—	benign
rs76171639	4:104,579,710	C/T	—	benign
rs180951745	4:104,579,827	G/A	—	likely benign
rs28878597	4:104,591,916	A/G	intron variant	—
rs10017280	4:104,609,388	C/T	intron variant	—
rs35518418	4:104,616,870	G/C	—	—
rs3796951	4:104,628,158	T/A	intron variant	—
rs28650409	4:104,628,577	C/T	intron variant	—
rs1905172	4:104,636,034	C/T	intron variant	—
rs73838916	4:104,639,997	C/T	—	benign
rs150915487	4:104,640,042	C/G	—	likely benign
rs150048847	4:104,640,233	A/G	—	likely benign
rs772508077	4:104,640,283	A/G	splice region variant	pathogenic
rs747474756	4:104,640,299	G/A	—	likely benign
rs199505146	4:104,640,319	T/C	—	uncertain significance
rs201195175	4:104,640,322	C/G	missense variant	pathogenic
rs750591352	4:104,640,388	T/C	—	uncertain significance
rs769086092	4:104,640,401	G/T	—	likely benign
rs1723155703	4:104,640,417	G/A	—	uncertain significance
rs773834697	4:104,640,429	G/A	—	uncertain significance
rs201808835	4:104,640,530	C/T	—	benign
rs771648268	4:104,640,536	T/A	—	likely benign
rs146498209	4:104,640,539	C/G	—	likely benign
rs121918124	4:104,640,555	C/T	missense variant	pathogenic
rs200917910	4:104,640,557	A/G	—	likely benign
rs1208727441	4:104,640,583	G/T	—	uncertain significance
rs1723160184	4:104,640,598	C/T	—	uncertain significance

Showing 100 of 115 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.