THOC5
THO complex subunit 5
Summary
Predicted to enable mRNA binding activity. Involved in mRNA export from nucleus and monocyte differentiation. Located in chromosome, telomeric region and nucleoplasm. Part of THO complex part of transcription export complex. Implicated in breast carcinoma. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants25 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs537289599 | 22:29,903,411 | C/T | — | — |
| rs139614127 | 22:29,904,501 | C/T | — | uncertain significance |
| rs55652051 | 22:29,905,277 | A/G | downstream gene variant | — |
| rs16987733 | 22:29,908,025 | G/A | — | benign |
| rs2063234462 | 22:29,908,037 | T/A | — | uncertain significance |
| rs768173834 | 22:29,913,057 | T/C | — | uncertain significance |
| rs35832657 | 22:29,913,278 | T/C | — | benign |
| rs763840864 | 22:29,915,028 | G/A | — | uncertain significance |
| rs761402487 | 22:29,915,058 | T/C | — | uncertain significance |
| rs2518036088 | 22:29,915,075 | C/A | — | uncertain significance |
| rs200435124 | 22:29,915,087 | G/A | — | uncertain significance |
| rs151070468 | 22:29,916,047 | A/T | — | uncertain significance |
| rs765353596 | 22:29,921,830 | G/A | — | uncertain significance |
| rs138718205 | 22:29,921,848 | A/G | — | uncertain significance |
| rs2518061758 | 22:29,921,886 | G/C | — | uncertain significance |
| rs769652979 | 22:29,924,079 | G/C | — | uncertain significance |
| rs188617925 | 22:29,924,118 | C/G | — | uncertain significance |
| rs986942532 | 22:29,924,435 | C/G | — | uncertain significance |
| rs576714272 | 22:29,925,205 | C/T | — | uncertain significance |
| rs2518087948 | 22:29,927,867 | G/A | — | uncertain significance |
| rs143914834 | 22:29,927,903 | T/C | — | uncertain significance |
| rs765796771 | 22:29,927,907 | C/T | — | uncertain significance |
| rs8135828 | 22:29,929,239 | G/A | intron variant | — |
| rs200573702 | 22:29,935,380 | T/C | — | uncertain significance |
| rs780430300 | 22:29,935,444 | A/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.