TMC7
transmembrane channel like 7
Summary
Predicted to enable ion channel inhibitor activity and mechanosensitive monoatomic ion channel activity. Predicted to be involved in sensory perception of mechanical stimulus. Predicted to be located in plasma membrane. Predicted to be active in neuronal cell body. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants59 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs781173030 | 16:18,995,396 | C/A | — | uncertain significance |
| rs1033376311 | 16:18,995,426 | C/T | — | uncertain significance |
| rs777003939 | 16:18,995,432 | G/A | — | uncertain significance |
| rs144721899 | 16:19,005,211 | A/G | intron variant | — |
| rs200026312 | 16:19,020,520 | T/C | — | uncertain significance |
| rs758568496 | 16:19,020,566 | G/A | — | uncertain significance |
| rs762260479 | 16:19,020,602 | G/A | — | uncertain significance |
| rs202073301 | 16:19,020,727 | C/T | — | uncertain significance |
| rs752176889 | 16:19,027,780 | A/C | — | uncertain significance |
| rs902380776 | 16:19,027,840 | C/T | — | uncertain significance |
| rs773139379 | 16:19,027,867 | G/A | — | uncertain significance |
| rs375541654 | 16:19,027,885 | T/A | — | uncertain significance |
| rs752696077 | 16:19,027,896 | C/T | — | uncertain significance |
| rs368588877 | 16:19,027,909 | G/A | — | uncertain significance |
| rs2509119323 | 16:19,027,915 | T/C | — | uncertain significance |
| rs4265793 | 16:19,028,549 | T/A | — | — |
| rs763506692 | 16:19,033,061 | C/T | — | uncertain significance |
| rs147994584 | 16:19,034,482 | T/A | — | uncertain significance |
| rs527628140 | 16:19,034,513 | G/A | — | uncertain significance |
| rs374745847 | 16:19,041,576 | G/A | — | uncertain significance |
| rs762167845 | 16:19,041,619 | A/G | — | uncertain significance |
| rs773522471 | 16:19,041,624 | C/G | — | uncertain significance |
| rs375390148 | 16:19,041,651 | A/G | — | uncertain significance |
| rs1370141177 | 16:19,041,670 | G/A | — | uncertain significance |
| rs2509182766 | 16:19,047,006 | A/G | — | uncertain significance |
| rs775525026 | 16:19,047,085 | C/A | — | uncertain significance |
| rs769754817 | 16:19,047,098 | C/T | — | uncertain significance |
| rs752282682 | 16:19,047,131 | C/T | — | uncertain significance |
| rs755192654 | 16:19,049,259 | C/T | — | uncertain significance |
| rs767590084 | 16:19,049,260 | G/A | — | uncertain significance |
| rs1248393404 | 16:19,049,269 | C/G | — | uncertain significance |
| rs148734728 | 16:19,049,346 | T/C | — | uncertain significance |
| rs2509193178 | 16:19,049,355 | G/A | — | uncertain significance |
| rs2509193248 | 16:19,049,364 | A/G | — | uncertain significance |
| rs28695599 | 16:19,051,151 | A/G | intron variant | — |
| rs775850366 | 16:19,051,633 | G/A | — | uncertain significance |
| rs751392976 | 16:19,051,660 | C/T | — | uncertain significance |
| rs200081538 | 16:19,051,698 | A/G | — | uncertain significance |
| rs779534768 | 16:19,051,699 | T/A | — | uncertain significance |
| rs375939261 | 16:19,051,713 | A/T | — | uncertain significance |
| rs73528934 | 16:19,051,741 | G/A | — | benign |
| rs763875145 | 16:19,056,220 | G/A | — | uncertain significance |
| rs146919639 | 16:19,056,312 | A/C | — | uncertain significance |
| rs770737086 | 16:19,056,744 | G/A | — | uncertain significance |
| rs74790534 | 16:19,056,768 | C/T | — | benign |
| rs2509235840 | 16:19,058,412 | C/G | — | likely benign |
| rs2509236380 | 16:19,058,477 | A/G | — | uncertain significance |
| rs201258676 | 16:19,058,499 | C/T | — | likely benign |
| rs146407341 | 16:19,058,500 | G/A | — | uncertain significance |
| rs2509255316 | 16:19,063,110 | A/G | — | uncertain significance |
| rs769232729 | 16:19,063,131 | A/G | — | uncertain significance |
| rs571097481 | 16:19,067,890 | C/T | — | uncertain significance |
| rs766231320 | 16:19,067,920 | T/C | — | uncertain significance |
| rs774286557 | 16:19,067,932 | C/T | — | uncertain significance |
| rs1371478486 | 16:19,067,974 | G/A | — | uncertain significance |
| rs1336536272 | 16:19,067,989 | C/G | — | uncertain significance |
| rs1383967703 | 16:19,067,995 | C/T | — | uncertain significance |
| rs374940794 | 16:19,070,782 | G/A | — | uncertain significance |
| rs1185596722 | 16:19,073,106 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.