rs144721899
This is a intron variant variant in the TMC7 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
Herpes Zoster
Stanaway IB et al. “The eMERGE genotype set of 83,717 subjects imputed to ~40 million variants genome wide and association with the herpes zoster medical record phenotype.” Genetic Epidemiology 43(1):63-81 (2019)
Allele G
OR 4.65
p 6.0e-9
N 45,237
Large GWAS
multi-ancestry
About TMC7
Predicted to enable ion channel inhibitor activity and mechanosensitive monoatomic ion channel activity. Predicted to be involved in sensory perception of mechanical stimulus. Predicted to be located in plasma membrane. Predicted to be active in neuronal cell body. [provided by Alliance of Genome Resources, Jul 2025]
View all TMC7 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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