TNFRSF10D
TNF receptor superfamily member 10d
Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]
Known Variants32 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs557200270 | 8:22,995,438 | G/A | — | uncertain significance |
| rs771299446 | 8:22,995,506 | C/A | — | uncertain significance |
| rs34622674 | 8:22,995,511 | T/G | — | benign |
| rs7011559 | 8:22,996,308 | A/T | — | — |
| rs774564849 | 8:23,001,977 | G/A | — | uncertain significance |
| rs1133782 | 8:23,001,988 | G/A | — | benign |
| rs116710124 | 8:23,002,045 | G/C | — | benign |
| rs777709638 | 8:23,002,085 | C/T | — | uncertain significance |
| rs1025226047 | 8:23,002,096 | T/C | — | uncertain significance |
| rs149257537 | 8:23,002,105 | G/A | — | uncertain significance |
| rs191751553 | 8:23,002,117 | C/T | — | likely benign |
| rs753830401 | 8:23,002,132 | C/T | — | uncertain significance |
| rs201357503 | 8:23,003,235 | C/A | — | uncertain significance |
| rs1585259747 | 8:23,003,258 | A/C | — | uncertain significance |
| rs750141413 | 8:23,003,316 | T/A | — | uncertain significance |
| rs542233972 | 8:23,003,399 | G/A | — | uncertain significance |
| rs61736092 | 8:23,004,539 | A/G | — | benign |
| rs193201133 | 8:23,004,544 | C/T | — | uncertain significance |
| rs201641657 | 8:23,004,570 | C/T | — | uncertain significance |
| rs749266965 | 8:23,005,999 | C/T | — | uncertain significance |
| rs111470087 | 8:23,006,470 | A/G | intron variant | — |
| rs7014637 | 8:23,009,137 | A/C | intron variant | — |
| rs1800255286 | 8:23,012,431 | G/A | — | uncertain significance |
| rs1459531779 | 8:23,012,469 | G/C | — | uncertain significance |
| rs143066323 | 8:23,012,480 | A/G | — | uncertain significance |
| rs372726522 | 8:23,012,488 | C/T | — | likely benign |
| rs73222560 | 8:23,017,235 | C/T | intron variant | — |
| rs200239385 | 8:23,021,263 | G/T | regulatory region variant | — |
| rs1800410173 | 8:23,021,303 | A/C | — | uncertain significance |
| rs1800410220 | 8:23,021,304 | G/T | — | uncertain significance |
| rs752548144 | 8:23,021,358 | A/G | — | uncertain significance |
| rs562406294 | 8:23,021,439 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.