rs7014637
This is a intron variant variant in the TNFRSF10D gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
asthma
Chang X et al. “Genetic architecture of asthma in African American patients.” The Journal of Allergy and Clinical Immunology 151(4):1132-1136 (2023)
Allele A
OR 0.06
p 2.0e-8
N 19,628
Large GWAS
African American or Afro-Caribbean
About TNFRSF10D
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]
View all TNFRSF10D variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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