TRAF3IP1

TRAF3 interacting protein 1

Summary

The protein encoded by this gene interacts with TNF receptor-associated factor 3, tethering it to cytoskeletal microtubules. The encoded protein is also an inhibitor of the innate type I IFN response. Defects in this gene are a cause of Senior-Loken syndrome 9. [provided by RefSeq, Mar 2017]

Known Variants506 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs113517613	2:239,229,029	C/A	—	benign
rs1559349524	2:239,229,306	G/T	—	uncertain significance
rs1697476086	2:239,229,311	C/G	—	uncertain significance
rs2106351680	2:239,229,321	G/A	—	likely benign
rs1697477035	2:239,229,325	C/T	—	uncertain significance
rs537545949	2:239,229,326	G/A	—	uncertain significance
rs1214100414	2:239,229,329	C/G	—	uncertain significance
rs1425255419	2:239,229,337	G/T	—	uncertain significance
rs766609697	2:239,229,345	G/C	—	likely benign
rs1357364279	2:239,229,347	A/G	—	uncertain significance
rs886037899	2:239,229,354	T/G	missense variant	pathogenic
rs1238300900	2:239,229,355	C/T	—	uncertain significance
rs1277049217	2:239,229,359	G/T	—	uncertain significance
rs1442403482	2:239,229,360	G/T	—	uncertain significance
rs1413908284	2:239,229,371	C/T	—	uncertain significance
rs13398676	2:239,229,372	C/G	—	likely benign
rs1256966921	2:239,229,391	C/T	—	uncertain significance
rs752772495	2:239,229,392	C/T	—	uncertain significance
rs1183349435	2:239,229,393	C/G	—	likely benign
rs758608986	2:239,229,396	G/A	—	likely benign
rs778071226	2:239,229,399	C/T	—	likely benign
rs1463811196	2:239,229,404	A/G	—	uncertain significance
rs2469587533	2:239,229,405	C/T	—	likely benign
rs747134709	2:239,229,406	C/T	—	likely benign
rs2469587591	2:239,229,411	C/T	—	likely benign
rs2469587669	2:239,229,417	C/T	—	likely benign
rs370097041	2:239,229,418	A/G	—	uncertain significance
rs1467416546	2:239,229,420	C/T	—	likely benign
rs1225876583	2:239,229,421	A/G	—	uncertain significance
rs1321646396	2:239,229,427	G/T	—	likely pathogenic
rs1330543079	2:239,229,436	G/A	—	likely benign
rs112673616	2:239,229,440	A/G	—	benign
rs1339116838	2:239,229,442	C/A	—	likely benign
rs1218396717	2:239,229,443	G/A	—	likely benign
rs3739071	2:239,229,580	G/A	—	benign
rs6716870	2:239,229,644	G/A	—	benign
rs7566151	2:239,231,738	T/C	—	—
rs4663304	2:239,233,732	T/C	—	benign
rs758510046	2:239,233,932	C/T	—	likely benign
rs777675275	2:239,233,934	T/G	—	likely benign
rs1017902907	2:239,233,941	T/C	—	likely benign
rs1553609359	2:239,233,942	T/G	—	likely pathogenic
rs2106358531	2:239,233,968	A/C	—	uncertain significance
rs1574887966	2:239,233,975	G/A	—	uncertain significance
rs138861670	2:239,233,988	C/T	—	likely benign
rs138242959	2:239,233,991	C/T	—	likely benign
rs769651861	2:239,233,992	G/A	—	pathogenic
rs2106358575	2:239,233,996	T/C	—	uncertain significance
rs1419203342	2:239,234,000	G/A	—	likely benign
rs1274634129	2:239,234,009	T/C	—	likely benign
rs1697771953	2:239,234,016	G/C	—	likely pathogenic
rs1327817445	2:239,234,026	G/A	—	likely benign
rs780142193	2:239,234,028	C/T	—	likely benign
rs749136615	2:239,234,029	G/A	—	likely benign
rs1339474787	2:239,234,030	G/A	—	likely benign
rs1406208996	2:239,234,031	G/A	—	likely benign
rs2469601980	2:239,234,034	T/C	—	likely benign
rs6723560	2:239,234,109	T/C	—	benign
rs75651012	2:239,234,396	A/G	—	benign
rs200790597	2:239,234,433	C/G	—	likely benign
rs2469603440	2:239,234,434	A/C	—	likely benign
rs769747839	2:239,234,443	G/A	—	likely benign
rs1255365750	2:239,234,450	G/C	—	uncertain significance
rs2106359225	2:239,234,459	G/A	—	uncertain significance
rs879162414	2:239,234,469	G/C	—	uncertain significance
rs534435982	2:239,234,470	C/T	—	likely benign
rs2106359291	2:239,234,482	G/A	—	likely benign
rs754845026	2:239,234,485	C/A	—	likely benign
rs143375220	2:239,234,487	T/C	—	uncertain significance
rs377098968	2:239,234,491	C/T	—	likely benign
rs771514528	2:239,234,492	G/A	—	uncertain significance
rs562515570	2:239,234,501	A/G	—	uncertain significance
rs147512316	2:239,234,508	C/T	—	uncertain significance
rs369712115	2:239,234,509	G/A	—	likely benign
rs763584113	2:239,234,516	C/T	—	uncertain significance
rs137999499	2:239,234,520	T/A	—	uncertain significance
rs753575315	2:239,234,539	A/G	—	likely benign
rs1025631475	2:239,234,541	T/C	—	uncertain significance
rs372369730	2:239,234,542	C/T	—	likely benign
rs527454385	2:239,234,543	G/A	—	uncertain significance
rs748053310	2:239,234,547	C/T	—	uncertain significance
rs377279034	2:239,234,548	G/A	—	likely benign
rs759480850	2:239,234,550	G/T	—	uncertain significance
rs750200893	2:239,234,554	T/C	—	likely benign
rs1697808015	2:239,234,557	G/A	—	likely benign
rs768996128	2:239,234,572	C/T	—	likely benign
rs1363044681	2:239,234,573	G/A	—	uncertain significance
rs2469604266	2:239,234,579	C/T	—	uncertain significance
rs1406745027	2:239,234,583	A/C	—	uncertain significance
rs761049632	2:239,234,603	C/T	—	uncertain significance
rs369848312	2:239,234,628	G/C	—	likely benign
rs7568830	2:239,237,157	C/T	—	benign
rs2469612636	2:239,237,310	T/G	—	uncertain significance
rs369455001	2:239,237,320	C/T	—	likely benign
rs760057892	2:239,237,321	G/A	—	likely benign
rs2106363198	2:239,237,330	T/G	—	uncertain significance
rs759756954	2:239,237,334	G/C	—	uncertain significance
rs140265133	2:239,237,335	T/C	—	likely benign
rs752459680	2:239,237,338	C/T	—	likely benign
rs1160992349	2:239,237,341	T/A	—	uncertain significance

Showing 100 of 506 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.