TRIM40
tripartite motif containing 40
Summary
This gene encodes a member of the tripartite motif (TRIM) protein family. The encoded protein may play a role as a negative regulator against inflammation and carcinogenesis in the gastrointestinal tract. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]
Known Variants22 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs3094677 | 6:30,102,958 | T/A | upstream gene variant | — |
| rs141520003 | 6:30,104,816 | G/A | — | likely benign |
| rs748413092 | 6:30,104,845 | A/C | — | uncertain significance |
| rs2480925604 | 6:30,104,850 | G/A | — | likely benign |
| rs766862389 | 6:30,104,917 | G/A | — | uncertain significance |
| rs984589693 | 6:30,105,003 | G/C | — | uncertain significance |
| rs1361442798 | 6:30,105,060 | G/A | — | uncertain significance |
| rs199723848 | 6:30,105,087 | G/A | — | uncertain significance |
| rs146858612 | 6:30,105,103 | C/T | — | uncertain significance |
| rs28780086 | 6:30,105,154 | A/G | missense variant | — |
| rs2844789 | 6:30,112,795 | G/T | — | — |
| rs760838031 | 6:30,113,786 | C/T | — | uncertain significance |
| rs1771625030 | 6:30,113,823 | A/G | — | uncertain significance |
| rs148812542 | 6:30,113,847 | A/C | — | uncertain significance |
| rs2256146 | 6:30,114,307 | G/C | intron variant | — |
| rs3815079 | 6:30,114,365 | A/T | intron variant | — |
| rs3132124 | 6:30,114,402 | A/T | intron variant | — |
| rs771907760 | 6:30,114,859 | G/A | — | likely benign |
| rs200282002 | 6:30,114,960 | A/G | — | uncertain significance |
| rs139222511 | 6:30,114,976 | A/G | — | likely benign |
| rs144156037 | 6:30,115,153 | G/A | downstream gene variant | — |
| rs115651142 | 6:30,115,320 | G/T | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.