rs115651142
This variant is located in the TRIM40 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
protein measurement
Western D et al. “Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.” Nature Genetics 56(12):2672-2684 (2024)
Allele T
OR 0.78
p 1.0e-15
N 3,506
Large GWAS
European
▶ClinVar annotation
Benign★☆☆☆
2 submitters1 publicationnot provided; Gastric cancer; Clear cell carcinoma of kidney; Colon adenocarcinoma
View on ClinVar →About TRIM40
This gene encodes a member of the tripartite motif (TRIM) protein family. The encoded protein may play a role as a negative regulator against inflammation and carcinogenesis in the gastrointestinal tract. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]
View all TRIM40 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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