TRIM58
tripartite motif containing 58
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants40 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1037085742 | 1:248,020,555 | T/C | — | uncertain significance |
| rs11204523 | 1:248,020,556 | G/T | missense variant | — |
| rs761684693 | 1:248,020,558 | G/A | — | uncertain significance |
| rs1034372922 | 1:248,020,567 | G/C | — | uncertain significance |
| rs758862161 | 1:248,020,573 | C/T | — | uncertain significance |
| rs755397625 | 1:248,020,763 | A/G | — | uncertain significance |
| rs903136281 | 1:248,020,825 | G/A | — | uncertain significance |
| rs765903580 | 1:248,020,889 | T/C | — | uncertain significance |
| rs566348638 | 1:248,020,946 | A/T | — | uncertain significance |
| rs57248897 | 1:248,022,712 | C/T | — | — |
| rs139660935 | 1:248,023,923 | A/G | — | uncertain significance |
| rs2527616023 | 1:248,023,941 | A/T | — | uncertain significance |
| rs750487447 | 1:248,023,986 | A/G | — | likely benign |
| rs3737276 | 1:248,024,073 | A/G | — | — |
| rs368652011 | 1:248,028,031 | C/T | — | uncertain significance |
| rs767483764 | 1:248,028,107 | C/T | — | uncertain significance |
| rs749714512 | 1:248,028,134 | T/G | — | uncertain significance |
| rs12061165 | 1:248,028,968 | G/C | upstream gene variant | — |
| rs12062391 | 1:248,029,483 | G/C | — | — |
| rs12027924 | 1:248,029,658 | C/A | — | — |
| rs746967497 | 1:248,031,315 | A/G | — | likely benign |
| rs12123108 | 1:248,033,282 | A/C | — | — |
| rs574260195 | 1:248,036,269 | C/T | — | — |
| rs182024931 | 1:248,036,303 | C/T | intron variant | — |
| rs9803874 | 1:248,037,278 | G/T | — | — |
| rs4925748 | 1:248,038,197 | A/C | — | — |
| rs4925750 | 1:248,038,325 | T/C | intron variant | — |
| rs200948948 | 1:248,039,252 | G/A | — | uncertain significance |
| rs1225478844 | 1:248,039,289 | G/A | — | uncertain significance |
| rs1312152087 | 1:248,039,291 | G/C | — | uncertain significance |
| rs140835435 | 1:248,039,343 | T/C | — | uncertain significance |
| rs143395933 | 1:248,039,432 | C/T | — | uncertain significance |
| rs770461236 | 1:248,039,433 | C/G | — | uncertain significance |
| rs3811444 | 1:248,039,451 | C/T | missense variant | — |
| rs1192337108 | 1:248,039,460 | C/T | — | uncertain significance |
| rs757927018 | 1:248,039,489 | C/A | — | uncertain significance |
| rs1223578784 | 1:248,039,537 | C/T | — | uncertain significance |
| rs2527656109 | 1:248,039,567 | A/G | — | uncertain significance |
| rs1377807664 | 1:248,039,655 | G/T | — | uncertain significance |
| rs10888263 | 1:248,041,182 | T/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.