rs9803874

This variant is located in the TRIM58 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

level of cytoplasmic dynein 1 heavy chain 1 in blood

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.10

p 4.0e-43

N 47,745

Large GWAS

European

dynein light chain Tctex-type 3 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.10

p 6.0e-43

N 47,745

Large GWAS

European

About TRIM58

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response and regulation of gene expression. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all TRIM58 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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