TSHZ2
teashirt zinc finger homeobox 2
Summary
This gene is a member of the teashirt C2H2-type zinc-finger protein family of transcription factors. This gene encodes a protein with five C2H2-type zinc fingers, a homeobox DNA-binding domain and a coiled-coil domain. This nuclear protein is predicted to act as a transcriptional repressor. This gene is thought to play a role in the development and progression of breast and other types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Known Variants80 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs57139429 | 20:51,587,111 | A/G | upstream gene variant | — |
| rs1892203 | 20:51,696,096 | C/T | regulatory region variant | — |
| rs2747399 | 20:51,707,666 | G/A | intron variant | — |
| rs1293430 | 20:51,734,779 | T/G | intron variant | — |
| rs11696852 | 20:51,770,946 | C/T | intron variant | — |
| rs118174081 | 20:51,778,123 | C/T | regulatory region variant | — |
| rs148188030 | 20:51,779,041 | A/G | regulatory region variant | — |
| rs201799053 | 20:51,870,106 | G/A | — | uncertain significance |
| rs776722470 | 20:51,870,148 | G/A | — | uncertain significance |
| rs774303094 | 20:51,870,155 | A/C | — | uncertain significance |
| rs146937231 | 20:51,870,169 | C/T | — | uncertain significance |
| rs373712084 | 20:51,870,173 | A/G | — | uncertain significance |
| rs2516043220 | 20:51,870,198 | G/C | — | uncertain significance |
| rs202246859 | 20:51,870,244 | T/G | — | likely benign |
| rs370871141 | 20:51,870,279 | C/G | — | uncertain significance |
| rs45448297 | 20:51,870,295 | G/A | — | uncertain significance |
| rs2516043765 | 20:51,870,301 | G/C | — | uncertain significance |
| rs1043741335 | 20:51,870,302 | A/G | — | uncertain significance |
| rs772860713 | 20:51,870,356 | A/G | — | uncertain significance |
| rs778096115 | 20:51,870,379 | G/C | — | uncertain significance |
| rs1007862852 | 20:51,870,508 | G/C | — | uncertain significance |
| rs745314478 | 20:51,870,534 | G/C | — | uncertain significance |
| rs149724132 | 20:51,870,548 | G/A | — | uncertain significance |
| rs370108973 | 20:51,870,565 | A/G | — | uncertain significance |
| rs1451620858 | 20:51,870,659 | G/C | — | uncertain significance |
| rs147561098 | 20:51,870,662 | C/T | — | uncertain significance |
| rs1354508681 | 20:51,870,716 | A/G | — | uncertain significance |
| rs773611865 | 20:51,870,731 | G/A | — | uncertain significance |
| rs141985599 | 20:51,870,755 | C/T | — | uncertain significance |
| rs780826702 | 20:51,870,841 | G/A | — | uncertain significance |
| rs142965743 | 20:51,870,845 | C/T | — | uncertain significance |
| rs138844500 | 20:51,870,967 | G/A | — | uncertain significance |
| rs1990416766 | 20:51,871,010 | G/T | — | uncertain significance |
| rs528853616 | 20:51,871,045 | G/A | — | uncertain significance |
| rs777536124 | 20:51,871,072 | C/T | — | uncertain significance |
| rs372519804 | 20:51,871,187 | C/T | — | uncertain significance |
| rs2516048572 | 20:51,871,190 | A/C | — | uncertain significance |
| rs915108110 | 20:51,871,216 | A/C | — | uncertain significance |
| rs1187349556 | 20:51,871,255 | G/C | — | uncertain significance |
| rs778769992 | 20:51,871,286 | A/T | — | likely benign |
| rs200752097 | 20:51,871,441 | G/A | — | uncertain significance |
| rs368899655 | 20:51,871,448 | A/G | — | uncertain significance |
| rs750530620 | 20:51,871,465 | A/C | — | uncertain significance |
| rs146846054 | 20:51,871,636 | G/T | — | uncertain significance |
| rs777134610 | 20:51,871,664 | C/T | — | uncertain significance |
| rs2516050848 | 20:51,871,678 | G/A | — | uncertain significance |
| rs145683350 | 20:51,871,699 | C/T | — | uncertain significance |
| rs372347557 | 20:51,871,700 | G/A | — | uncertain significance |
| rs543394530 | 20:51,871,712 | C/T | — | uncertain significance |
| rs1404898083 | 20:51,871,773 | A/G | — | likely benign |
| rs746587508 | 20:51,871,774 | C/T | — | uncertain significance |
| rs138624451 | 20:51,871,781 | C/T | — | uncertain significance |
| rs149322518 | 20:51,871,801 | A/G | — | uncertain significance |
| rs147158776 | 20:51,871,858 | G/A | — | uncertain significance |
| rs1568837936 | 20:51,871,967 | T/A | — | uncertain significance |
| rs200539548 | 20:51,872,051 | A/G | — | uncertain significance |
| rs757806984 | 20:51,872,057 | C/T | — | uncertain significance |
| rs867002096 | 20:51,872,096 | C/T | — | uncertain significance |
| rs755119289 | 20:51,872,098 | G/A | — | uncertain significance |
| rs771576075 | 20:51,872,135 | T/C | — | uncertain significance |
| rs751777308 | 20:51,872,169 | C/G | — | uncertain significance |
| rs779015904 | 20:51,872,192 | C/T | — | uncertain significance |
| rs550457475 | 20:51,872,207 | T/G | — | uncertain significance |
| rs147000485 | 20:51,872,251 | G/A | — | uncertain significance |
| rs779892655 | 20:51,872,260 | C/T | — | uncertain significance |
| rs143580078 | 20:51,872,330 | C/T | — | uncertain significance |
| rs1990461659 | 20:51,872,345 | G/A | — | uncertain significance |
| rs1243358036 | 20:51,872,360 | A/G | — | uncertain significance |
| rs776713281 | 20:51,872,398 | G/A | — | uncertain significance |
| rs375595323 | 20:51,872,413 | A/G | — | uncertain significance |
| rs1013512791 | 20:51,872,414 | C/G | — | uncertain significance |
| rs1417791833 | 20:51,872,450 | C/T | — | uncertain significance |
| rs747386791 | 20:51,872,457 | G/T | — | uncertain significance |
| rs781658976 | 20:51,872,582 | C/T | — | uncertain significance |
| rs752955524 | 20:51,872,782 | A/G | — | uncertain significance |
| rs368192582 | 20:51,872,912 | C/G | — | uncertain significance |
| rs1347452212 | 20:51,872,939 | C/G | — | uncertain significance |
| rs1243217012 | 20:51,872,998 | C/T | — | uncertain significance |
| rs200356396 | 20:51,873,044 | C/T | — | uncertain significance |
| rs1057509217 | 20:52,099,293 | A/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.