UNC45A

unc-45 myosin chaperone A

Summary

This gene encodes a regulatory component of the progesterone receptor/heat shock protein 90 chaperoning complex, which functions in the assembly and folding of the progesterone receptor. The encoded protein is thought to be essential for normal cell proliferation, and for the accumulation of myosin during development of muscle cells. [provided by RefSeq, Sep 2018]

Known Variants528 total

rsidPosition (GRCh37)AllelesClassClinVar
rs135623251715:91,478,457G/T—conflicting classifications of pathogenicity
rs96435130915:91,478,558A/G—uncertain significance
rs77108094715:91,478,577C/T—uncertain significance
rs77577088315:91,478,584G/T—uncertain significance
rs57271825315:91,478,585C/T—uncertain significance
rs20203160915:91,478,586C/T—uncertain significance
rs20087630015:91,478,587C/A—likely benign
rs75006835415:91,478,589G/C—uncertain significance
rs75577023015:91,478,590G/A—likely benign
rs37065404915:91,478,598C/T—uncertain significance
rs141031815015:91,478,602C/T—likely benign
rs159620647415:91,478,607T/C—likely pathogenic
rs37414081215:91,478,610G/A—conflicting classifications of pathogenicity
rs92657611515:91,478,613C/A—likely benign
rs77099749515:91,478,618C/T—likely benign
rs78015583315:91,478,759C/T—likely benign
rs116329038615:91,478,766C/T—likely benign
rs14963221915:91,478,777A/G—uncertain significance
rs254311486715:91,478,793T/G—uncertain significance
rs75927703615:91,478,800G/A—likely benign
rs203596740715:91,478,809T/C—likely benign
rs75251319815:91,478,812G/A—likely benign
rs92938561515:91,478,839C/A—likely benign
rs215135353615:91,478,841C/A—conflicting classifications of pathogenicity
rs129127793715:91,478,866G/A—likely benign
rs130285991015:91,478,875C/G—uncertain significance
rs77357648215:91,478,878G/C—likely benign
rs95442563815:91,478,890C/T—likely benign
rs75676087815:91,478,913G/A—uncertain significance
rs128676993815:91,478,917C/T—likely benign
rs77833646315:91,478,932G/A—likely benign
rs254311595715:91,478,936G/C—likely pathogenic
rs126779893115:91,478,945C/A—likely benign
rs215135373115:91,478,948G/A—likely benign
rs14444143315:91,479,158C/T—likely benign
rs75509210915:91,479,168T/C—likely benign
rs254311737415:91,479,169C/T—likely benign
rs20127333715:91,479,185G/A—uncertain significance
rs118297556415:91,479,195A/T—uncertain significance
rs138255192715:91,479,199A/G—likely benign
rs144626757415:91,479,207C/G—uncertain significance
rs54090546515:91,479,208C/A—likely benign
rs215135423715:91,479,209A/C—uncertain significance
rs141439354215:91,479,217G/A—uncertain significance
rs37643153715:91,479,495G/A—likely benign
rs132032260715:91,479,500C/T—likely benign
rs254311940515:91,479,510C/T—likely benign
rs203601474815:91,479,518T/C—uncertain significance
rs98740257415:91,479,521A/G—uncertain significance
rs14066478715:91,479,525G/A—likely benign
rs203601605515:91,479,533G/C—uncertain significance
rs92917508115:91,479,537T/A—uncertain significance
rs203601747515:91,479,549C/T—likely benign
rs140815762715:91,479,551A/G—uncertain significance
rs14300928815:91,479,553C/T—uncertain significance
rs36910391115:91,479,556C/T—uncertain significance
rs20045647715:91,479,557G/A—uncertain significance
rs143200963315:91,479,566C/A—uncertain significance
rs148104285515:91,479,569T/C—uncertain significance
rs74879986015:91,479,583C/T—uncertain significance
rs140372617915:91,479,586C/G—uncertain significance
rs215135502515:91,479,591C/T—likely benign
rs144629248615:91,479,607C/T—likely benign
rs77186513415:91,479,614G/C—uncertain significance
rs254312002615:91,479,615A/T—uncertain significance
rs76063818315:91,479,619G/A—uncertain significance
rs76311079315:91,479,628G/C—uncertain significance
rs104662833815:91,479,631C/G—uncertain significance
rs76414096415:91,479,635A/C—uncertain significance
rs88666073215:91,479,642A/G—likely benign
rs37385414315:91,479,644T/G—uncertain significance
rs131973324215:91,479,649C/T—uncertain significance
rs54973065415:91,479,661C/T—uncertain significance
rs14748134515:91,479,662G/A—likely benign
rs19983189615:91,479,669C/T—benign
rs121376079515:91,479,671G/C—uncertain significance
rs138185263515:91,479,672G/A—likely benign
rs203602777315:91,479,680T/C—uncertain significance
rs254312038215:91,479,684G/A—likely benign
rs56813844015:91,479,688A/C—uncertain significance
rs77093941315:91,479,701G/C—likely benign
rs215135523615:91,479,703C/T—likely benign
rs1290444515:91,480,010C/G——
rs77758425815:91,482,941T/C—likely benign
rs19957750215:91,482,944T/C—benign
rs75711837415:91,482,951G/C—likely benign
rs14854588215:91,482,965G/A—uncertain significance
rs254312848315:91,482,969C/T—likely benign
rs20073658615:91,482,977C/T—uncertain significance
rs77445198815:91,482,978G/C—likely benign
rs14215425515:91,482,980C/T—uncertain significance
rs142855569315:91,482,996A/G—likely benign
rs215135896515:91,482,998A/G—uncertain significance
rs76670522015:91,483,001T/G—uncertain significance
rs15120455715:91,483,002G/A—uncertain significance
rs76566328015:91,483,014G/A—likely benign
rs126490581415:91,483,020C/A—uncertain significance
rs203619766815:91,483,033G/A—uncertain significance
rs254312879415:91,483,042A/C—uncertain significance
rs75122598715:91,483,047G/C—uncertain significance

Showing 100 of 528 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.