USP3
ubiquitin specific peptidase 3
Summary
Enables deubiquitinase activity and histone binding activity. Involved in DNA repair and DNA repair-dependent chromatin remodeling. Located in several cellular components, including Flemming body; cytoplasmic ribonucleoprotein granule; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants38 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs11638671 | 15:63,795,628 | T/C | regulatory region variant | — |
| rs2550681653 | 15:63,796,979 | C/A | — | uncertain significance |
| rs74519289 | 15:63,802,482 | A/C | regulatory region variant | — |
| rs146311723 | 15:63,804,507 | T/C | intron variant | — |
| rs78473652 | 15:63,806,935 | A/T | regulatory region variant | — |
| rs62011302 | 15:63,813,743 | G/A | intron variant | — |
| rs79488359 | 15:63,818,005 | T/G | intron variant | — |
| rs2550695427 | 15:63,824,859 | C/A | — | uncertain significance |
| rs1308985995 | 15:63,829,277 | C/G | — | uncertain significance |
| rs768767849 | 15:63,829,289 | A/G | — | uncertain significance |
| rs201119432 | 15:63,829,349 | C/T | — | uncertain significance |
| rs113722928 | 15:63,834,771 | A/G | downstream gene variant | — |
| rs1338299537 | 15:63,845,918 | C/T | — | uncertain significance |
| rs754104447 | 15:63,850,309 | G/C | — | uncertain significance |
| rs1243983170 | 15:63,855,104 | G/A | — | uncertain significance |
| rs2550724981 | 15:63,862,664 | T/C | — | uncertain significance |
| rs199612777 | 15:63,862,705 | G/A | — | uncertain significance |
| rs777976100 | 15:63,862,715 | G/C | — | uncertain significance |
| rs764701879 | 15:63,866,253 | C/A | — | uncertain significance |
| rs372352635 | 15:63,866,273 | A/G | — | uncertain significance |
| rs2066822697 | 15:63,866,277 | T/G | — | uncertain significance |
| rs773694739 | 15:63,866,331 | G/C | — | uncertain significance |
| rs770724178 | 15:63,866,560 | C/T | — | uncertain significance |
| rs34776764 | 15:63,866,584 | C/A | — | benign |
| rs74018128 | 15:63,866,708 | G/A | — | — |
| rs62012772 | 15:63,866,877 | T/C | intron variant | — |
| rs7168903 | 15:63,873,268 | A/G | intron variant | — |
| rs12907106 | 15:63,873,658 | C/T | — | — |
| rs146583283 | 15:63,880,614 | C/T | — | benign |
| rs139639201 | 15:63,880,962 | C/T | — | uncertain significance |
| rs201397735 | 15:63,880,967 | G/A | — | uncertain significance |
| rs761956783 | 15:63,881,000 | T/C | — | uncertain significance |
| rs370216924 | 15:63,881,162 | A/G | — | uncertain significance |
| rs763688428 | 15:63,881,209 | G/A | — | uncertain significance |
| rs2550745813 | 15:63,882,880 | C/T | — | uncertain significance |
| rs34527287 | 15:63,882,944 | C/T | — | benign |
| rs748047714 | 15:63,883,011 | T/C | — | uncertain significance |
| rs773875927 | 15:63,883,020 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.