rs62011302

This is a intron variant variant in the USP3 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

sex hormone-binding globulin measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.03
p 8.0e-15
N 322,484
Major Consortium StudyLarge GWAS
multi-ancestry

bilirubin measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 4.0e-13
N 354,368
Major Consortium StudyLarge GWAS
multi-ancestry

vitamin D level

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele A
OR 0.02
p 2.0e-9
N 339,705
Major Consortium StudyLarge GWAS
multi-ancestry

About USP3

Enables deubiquitinase activity and histone binding activity. Involved in DNA repair and DNA repair-dependent chromatin remodeling. Located in several cellular components, including Flemming body; cytoplasmic ribonucleoprotein granule; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

View all USP3 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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