USP39
ubiquitin specific peptidase 39
Summary
Predicted to enable cysteine-type deubiquitinase activity and zinc ion binding activity. Involved in spliceosomal complex assembly. Located in nucleoplasm. Part of U4/U6 x U5 tri-snRNP complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants39 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs143452153 | 2:85,832,897 | G/C | regulatory region variant | — |
| rs192437130 | 2:85,840,200 | C/T | upstream gene variant | — |
| rs753021536 | 2:85,843,325 | G/A | — | likely benign |
| rs781741366 | 2:85,843,341 | A/G | — | uncertain significance |
| rs755706376 | 2:85,843,349 | G/A | — | uncertain significance |
| rs779369298 | 2:85,843,358 | C/T | — | uncertain significance |
| rs1044529615 | 2:85,843,392 | C/T | — | uncertain significance |
| rs1165310963 | 2:85,843,437 | C/T | — | uncertain significance |
| rs1390676663 | 2:85,843,442 | A/C | — | uncertain significance |
| rs968952197 | 2:85,843,452 | G/A | — | uncertain significance |
| rs754552396 | 2:85,843,475 | G/C | — | uncertain significance |
| rs746734029 | 2:85,843,491 | G/T | — | uncertain significance |
| rs370005784 | 2:85,843,544 | C/T | — | uncertain significance |
| rs781076069 | 2:85,843,550 | G/A | — | uncertain significance |
| rs573708460 | 2:85,845,951 | G/A | — | — |
| rs750066293 | 2:85,846,374 | G/C | — | likely benign |
| rs1674265695 | 2:85,846,381 | C/T | — | uncertain significance |
| rs2466461503 | 2:85,848,701 | A/T | — | uncertain significance |
| rs762147072 | 2:85,857,908 | A/G | — | uncertain significance |
| rs143539117 | 2:85,858,064 | A/G | — | uncertain significance |
| rs6547629 | 2:85,860,228 | A/G | — | — |
| rs546644168 | 2:85,863,120 | A/C | — | — |
| rs998576092 | 2:85,863,219 | C/G | — | uncertain significance |
| rs200622671 | 2:85,863,239 | A/G | — | uncertain significance |
| rs2466556955 | 2:85,864,492 | C/G | — | uncertain significance |
| rs191467712 | 2:85,865,754 | C/T | intron variant | — |
| rs192957129 | 2:85,867,558 | C/T | intron variant | — |
| rs1329352584 | 2:85,868,140 | G/C | — | uncertain significance |
| rs1450479837 | 2:85,868,195 | A/T | — | uncertain significance |
| rs75379470 | 2:85,869,116 | A/G | intron variant | — |
| rs778773531 | 2:85,872,075 | G/A | — | uncertain significance |
| rs374640624 | 2:85,872,133 | A/G | — | uncertain significance |
| rs763297712 | 2:85,872,174 | G/C | — | uncertain significance |
| rs72846629 | 2:85,873,907 | G/A | intron variant | — |
| rs58588820 | 2:85,874,044 | C/A | — | — |
| rs2466615454 | 2:85,875,092 | A/G | — | uncertain significance |
| rs1676837519 | 2:85,875,903 | A/G | — | uncertain significance |
| rs375627272 | 2:85,875,914 | A/G | — | uncertain significance |
| rs371581754 | 2:85,875,923 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.