VPS13C

vacuolar protein sorting 13 homolog C

Summary

Involved in mitochondrion organization and negative regulation of type 2 mitophagy. Located in several cellular components, including late endosome; lipid droplet; and mitochondrial outer membrane. Implicated in Parkinson's disease 23. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants847 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1723809615:62,146,598C/T—benign
rs55764778015:62,146,668T/C—benign
rs37537844815:62,146,677G/C—likely benign
rs90717779015:62,146,689T/G—likely benign
rs19073165715:62,146,706A/G—likely benign
rs76407183715:62,146,722C/T—likely benign
rs11581995115:62,146,742T/C—likely benign
rs77010247115:62,146,744G/T—uncertain significance
rs224149115:62,146,969T/A—benign
rs189381983215:62,147,056T/G—likely benign
rs37450025915:62,147,083G/T—uncertain significance
rs6200735815:62,147,087C/A—conflicting classifications of pathogenicity
rs214082853115:62,147,103T/G—likely benign
rs14344094415:62,147,116T/C—uncertain significance
rs76586747015:62,147,118A/T—uncertain significance
rs20188564715:62,147,146C/T—likely benign
rs11171059315:62,147,170A/G—benign
rs224149215:62,147,207T/A—benign
rs36817458815:62,148,482T/C—uncertain significance
rs214083216915:62,148,496T/C—uncertain significance
rs147675512615:62,148,504A/G—uncertain significance
rs76585453315:62,148,515G/A—likely benign
rs254778402115:62,148,530T/C—likely benign
rs76226405115:62,148,564C/T—uncertain significance
rs75883419715:62,148,580T/G—likely benign
rs14607219115:62,148,606C/T—conflicting classifications of pathogenicity
rs13884611815:62,148,607G/A—pathogenic
rs7342866115:62,148,781A/G—benign
rs127935372515:62,155,620T/C—likely benign
rs120820026515:62,155,652T/C—uncertain significance
rs75415982015:62,155,693C/T—uncertain significance
rs144035133315:62,155,741C/T—uncertain significance
rs14562329715:62,159,305G/A—uncertain significance
rs1259166715:62,160,742T/C—benign
rs716344115:62,160,758C/A—benign
rs75139082315:62,160,842G/A—likely benign
rs139299937315:62,160,870A/C—likely benign
rs7767374315:62,160,874C/T—benign
rs11622868515:62,160,901C/T—uncertain significance
rs254779890115:62,160,905T/C—uncertain significance
rs103324053415:62,160,928C/T—uncertain significance
rs75264672515:62,160,941G/A—uncertain significance
rs57000319315:62,160,963T/C—likely benign
rs52738365815:62,160,965C/A—pathogenic
rs1163665215:62,161,478A/G—benign
rs37698005315:62,161,681T/C—likely benign
rs75336989415:62,161,689A/G—likely benign
rs11620206515:62,161,707G/C—benign
rs116623460515:62,161,723C/G—uncertain significance
rs14686948015:62,161,737G/A—likely benign
rs76055763315:62,161,822C/T—uncertain significance
rs36821166915:62,164,173A/G—likely benign
rs75802006815:62,164,189T/C—conflicting classifications of pathogenicity
rs214087803015:62,164,214G/A—uncertain significance
rs1727119315:62,165,168A/Gintron variant—
rs189516395315:62,165,428T/C—likely benign
rs77900139315:62,165,447G/A—likely pathogenic
rs37611709615:62,165,469G/A—benign
rs254780549415:62,165,496C/T—likely benign
rs116973493115:62,165,500C/G—uncertain significance
rs135365887715:62,165,514T/G—uncertain significance
rs124804496915:62,165,515C/T—uncertain significance
rs1730388715:62,165,553T/C—benign
rs1730389415:62,165,577A/G—benign
rs37450086015:62,165,585G/A—conflicting classifications of pathogenicity
rs649429915:62,167,017G/A—benign
rs77938911015:62,167,060A/T—likely benign
rs189529895615:62,167,069A/C—likely benign
rs115705258615:62,167,074C/T—likely pathogenic
rs14451225515:62,167,076T/C—likely benign
rs145837739315:62,167,083T/C—uncertain significance
rs75584632315:62,167,161A/G—likely benign
rs74919990815:62,167,170A/T—likely benign
rs1270846915:62,167,897G/A—benign
rs36955722215:62,167,927A/G—uncertain significance
rs189537127915:62,167,931C/T—uncertain significance
rs254780975815:62,167,977C/T—uncertain significance
rs93624251615:62,167,985T/G—likely benign
rs254780993315:62,168,037T/A—uncertain significance
rs19149991615:62,168,050A/G—likely benign
rs15049696415:62,168,261A/G—benign
rs1107163415:62,169,072A/G—benign
rs54395637315:62,169,155C/T—benign
rs148806263915:62,169,161T/C—likely benign
rs75105485615:62,169,177C/A—pathogenic
rs14930756115:62,169,232T/C—likely benign
rs97417979015:62,169,248G/A—uncertain significance
rs36916812715:62,170,790C/G—likely benign
rs214089751615:62,170,827T/G—uncertain significance
rs118429599815:62,170,837T/G—uncertain significance
rs189563344715:62,170,853C/T—likely benign
rs19972346015:62,170,888C/A—pathogenic
rs145962754015:62,170,899T/C—uncertain significance
rs74820600515:62,170,918C/T—uncertain significance
rs14802110015:62,170,919G/A—likely benign
rs116952801315:62,170,931C/G—uncertain significance
rs77069161215:62,170,939A/G—likely benign
rs140836164315:62,170,949A/G—likely benign
rs1694467315:62,172,609A/G—benign
rs1290105515:62,172,907T/C—benign

Showing 100 of 847 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.