WIZ
WIZ zinc finger
Summary
Enables several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; histone methyltransferase binding activity; and transcription corepressor binding activity. Involved in positive regulation of nuclear cell cycle DNA replication and protein stabilization. Located in midbody and nucleoplasm. Biomarker of atherosclerosis. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants66 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1250428107 | 19:15,533,940 | G/A | — | uncertain significance |
| rs374817237 | 19:15,533,942 | G/A | — | uncertain significance |
| rs1290831770 | 19:15,533,943 | G/A | — | uncertain significance |
| rs2512821374 | 19:15,533,957 | G/C | — | uncertain significance |
| rs753728261 | 19:15,533,982 | G/A | — | uncertain significance |
| rs763206583 | 19:15,535,048 | G/C | — | uncertain significance |
| rs767950670 | 19:15,535,061 | G/C | — | uncertain significance |
| rs750949981 | 19:15,535,067 | G/A | — | uncertain significance |
| rs1481352203 | 19:15,535,088 | G/C | — | uncertain significance |
| rs199534121 | 19:15,535,097 | G/A | — | uncertain significance |
| rs527992086 | 19:15,535,151 | C/T | — | uncertain significance |
| rs1968575103 | 19:15,535,166 | G/A | — | uncertain significance |
| rs1330970924 | 19:15,535,169 | G/A | — | uncertain significance |
| rs778548938 | 19:15,535,438 | C/T | — | uncertain significance |
| rs770385117 | 19:15,535,471 | G/A | — | uncertain significance |
| rs1259303764 | 19:15,535,492 | T/C | — | uncertain significance |
| rs758203665 | 19:15,535,516 | G/C | — | uncertain significance |
| rs776151852 | 19:15,535,550 | C/T | — | uncertain significance |
| rs2512839511 | 19:15,535,552 | A/C | — | uncertain significance |
| rs199669830 | 19:15,535,588 | G/A | — | uncertain significance |
| rs779408177 | 19:15,535,601 | T/C | — | likely benign |
| rs200571537 | 19:15,535,649 | C/T | — | uncertain significance |
| rs1195020409 | 19:15,535,651 | C/T | — | uncertain significance |
| rs772510557 | 19:15,535,669 | T/C | — | uncertain significance |
| rs375354474 | 19:15,535,736 | C/T | — | uncertain significance |
| rs1295216912 | 19:15,536,208 | C/G | — | uncertain significance |
| rs775345511 | 19:15,536,222 | G/A | — | uncertain significance |
| rs775593222 | 19:15,536,229 | T/C | — | uncertain significance |
| rs777400604 | 19:15,536,277 | G/A | — | uncertain significance |
| rs757257564 | 19:15,536,283 | C/A | — | uncertain significance |
| rs2512853021 | 19:15,536,288 | G/A | — | uncertain significance |
| rs545526207 | 19:15,536,291 | G/A | — | uncertain significance |
| rs749445339 | 19:15,536,297 | G/A | — | uncertain significance |
| rs761882325 | 19:15,536,309 | T/C | — | uncertain significance |
| rs372587052 | 19:15,536,313 | C/T | — | likely benign |
| rs766620311 | 19:15,536,325 | C/T | — | uncertain significance |
| rs151280911 | 19:15,536,443 | C/T | — | likely benign |
| rs758544502 | 19:15,536,559 | G/A | — | uncertain significance |
| rs1329602365 | 19:15,536,573 | C/T | — | uncertain significance |
| rs781513451 | 19:15,536,574 | G/A | — | uncertain significance |
| rs200893760 | 19:15,537,868 | C/T | — | uncertain significance |
| rs750468909 | 19:15,537,873 | G/A | — | uncertain significance |
| rs758785602 | 19:15,538,014 | G/A | — | uncertain significance |
| rs776760394 | 19:15,538,020 | G/C | — | uncertain significance |
| rs760009177 | 19:15,538,023 | G/A | — | uncertain significance |
| rs748820922 | 19:15,538,024 | G/A | — | uncertain significance |
| rs532349846 | 19:15,538,042 | G/A | — | uncertain significance |
| rs773188946 | 19:15,538,050 | T/G | — | uncertain significance |
| rs770303567 | 19:15,538,068 | C/T | — | uncertain significance |
| rs201153156 | 19:15,538,069 | G/A | — | uncertain significance |
| rs2512878452 | 19:15,538,149 | G/A | — | uncertain significance |
| rs766027386 | 19:15,538,173 | C/T | — | uncertain significance |
| rs1224017757 | 19:15,538,260 | G/A | — | uncertain significance |
| rs757239626 | 19:15,538,309 | C/G | — | uncertain significance |
| rs751188789 | 19:15,538,314 | C/T | — | uncertain significance |
| rs780309121 | 19:15,538,324 | G/C | — | uncertain significance |
| rs554897536 | 19:15,539,054 | G/T | — | likely benign |
| rs186729461 | 19:15,547,078 | C/T | intron variant | — |
| rs2512965575 | 19:15,547,896 | A/T | — | uncertain significance |
| rs192898305 | 19:15,549,980 | G/A | — | likely benign |
| rs117240920 | 19:15,550,869 | C/T | intron variant | — |
| rs566346386 | 19:15,552,749 | C/T | — | — |
| rs1969984375 | 19:15,558,974 | A/G | — | uncertain significance |
| rs755989049 | 19:15,558,986 | G/A | — | uncertain significance |
| rs766016080 | 19:15,559,048 | G/A | — | uncertain significance |
| rs112163620 | 19:15,560,902 | C/G | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.