rs117240920
This is a intron variant variant in the WIZ gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
level of N-acetylmuramoyl-L-alanine amidase in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.31
p 6.0e-43
N 47,745
Large GWAS
European
About WIZ
Enables several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; histone methyltransferase binding activity; and transcription corepressor binding activity. Involved in positive regulation of nuclear cell cycle DNA replication and protein stabilization. Located in midbody and nucleoplasm. Biomarker of atherosclerosis. [provided by Alliance of Genome Resources, Jul 2025]
View all WIZ variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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