XKR4
XK related 4
Summary
Enables phospholipid scramblase activity. Involved in phosphatidylserine exposure on apoptotic cell surface. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants28 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs557951243 | 8:56,015,215 | C/G | — | uncertain significance |
| rs2486923072 | 8:56,015,277 | T/G | — | uncertain significance |
| rs893409248 | 8:56,015,362 | G/A | — | uncertain significance |
| rs748261375 | 8:56,015,436 | G/A | — | likely benign |
| rs573625053 | 8:56,015,487 | C/A | — | uncertain significance |
| rs2486923831 | 8:56,015,529 | G/A | — | uncertain significance |
| rs2486923899 | 8:56,015,560 | T/G | — | uncertain significance |
| rs565411277 | 8:56,015,578 | C/T | — | uncertain significance |
| rs749438952 | 8:56,015,617 | C/T | — | uncertain significance |
| rs1421753880 | 8:56,015,640 | G/A | — | likely benign |
| rs1196007630 | 8:56,015,721 | G/A | — | uncertain significance |
| rs754802998 | 8:56,015,745 | A/G | — | uncertain significance |
| rs1457450298 | 8:56,015,752 | G/C | — | uncertain significance |
| rs1585879009 | 8:56,015,766 | A/G | — | uncertain significance |
| rs540546007 | 8:56,071,513 | G/A | — | — |
| rs12542677 | 8:56,168,059 | C/T | intron variant | — |
| rs1803839589 | 8:56,270,249 | C/T | — | uncertain significance |
| rs576031126 | 8:56,285,973 | C/A | — | — |
| rs2622590 | 8:56,358,274 | G/A | downstream gene variant | — |
| rs62517386 | 8:56,375,915 | C/T | intron variant | — |
| rs768003479 | 8:56,435,938 | T/C | — | uncertain significance |
| rs759358828 | 8:56,436,313 | G/A | — | uncertain significance |
| rs2487113472 | 8:56,436,355 | A/G | — | uncertain significance |
| rs2487113559 | 8:56,436,410 | G/A | — | uncertain significance |
| rs771129861 | 8:56,436,453 | C/G | — | likely benign |
| rs140880948 | 8:56,436,510 | A/C | — | benign |
| rs370341934 | 8:56,436,697 | G/A | — | uncertain significance |
| rs2487114295 | 8:56,436,739 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.