ZAN
zonadhesin
Summary
This gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. The encoded protein is located in the acrosome and may be involved in signaling or gamete recognition. An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Known Variants196 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2406257 | 7:100,329,567 | G/T | — | — |
| rs111338114 | 7:100,330,492 | A/G | upstream gene variant | — |
| rs377089635 | 7:100,331,814 | T/C | — | uncertain significance |
| rs1418577792 | 7:100,331,841 | T/A | — | uncertain significance |
| rs2486388817 | 7:100,331,842 | C/A | — | likely benign |
| rs746189371 | 7:100,333,357 | C/T | — | likely benign |
| rs761235495 | 7:100,333,378 | G/A | — | likely benign |
| rs199612069 | 7:100,334,145 | C/T | — | benign |
| rs776645260 | 7:100,334,456 | C/T | — | uncertain significance |
| rs766074480 | 7:100,334,471 | G/A | — | uncertain significance |
| rs377492790 | 7:100,334,500 | G/A | — | likely benign |
| rs2486401726 | 7:100,334,515 | G/A | — | uncertain significance |
| rs747248793 | 7:100,334,603 | G/A | — | uncertain significance |
| rs200501007 | 7:100,334,605 | C/T | — | uncertain significance |
| rs201467036 | 7:100,334,608 | C/T | — | conflicting classifications of pathogenicity |
| rs1284499924 | 7:100,334,921 | C/A | — | uncertain significance |
| rs367593224 | 7:100,334,970 | G/A | — | uncertain significance |
| rs1172835552 | 7:100,336,090 | T/C | — | uncertain significance |
| rs370119698 | 7:100,336,124 | C/A | — | uncertain significance |
| rs201633210 | 7:100,336,151 | T/A | — | likely benign |
| rs1270048770 | 7:100,336,153 | C/T | — | uncertain significance |
| rs1807469839 | 7:100,336,183 | G/C | — | uncertain significance |
| rs747747456 | 7:100,336,203 | G/A | — | uncertain significance |
| rs557071363 | 7:100,341,270 | T/C | — | — |
| rs2484628058 | 7:100,344,209 | A/G | — | uncertain significance |
| rs2484629775 | 7:100,344,295 | G/T | — | uncertain significance |
| rs1808243949 | 7:100,344,298 | G/T | — | uncertain significance |
| rs376185033 | 7:100,344,306 | C/A | — | uncertain significance |
| rs2075671 | 7:100,345,106 | G/A | intron variant | — |
| rs762579546 | 7:100,345,248 | C/G | — | likely benign |
| rs1808324761 | 7:100,345,251 | T/A | — | uncertain significance |
| rs202133169 | 7:100,345,766 | G/A | — | uncertain significance |
| rs376834112 | 7:100,345,769 | G/A | — | uncertain significance |
| rs778436018 | 7:100,345,943 | C/G | — | likely benign |
| rs200460391 | 7:100,345,978 | C/T | — | likely benign |
| rs202196428 | 7:100,346,012 | G/C | — | uncertain significance |
| rs574016648 | 7:100,346,036 | G/A | — | uncertain significance |
| rs1460795010 | 7:100,346,052 | C/T | — | uncertain significance |
| rs79163323 | 7:100,346,053 | C/T | synonymous variant | — |
| rs1808388809 | 7:100,346,079 | G/T | — | uncertain significance |
| rs201666374 | 7:100,348,276 | C/T | — | likely benign |
| rs769543736 | 7:100,348,316 | C/T | — | uncertain significance |
| rs546327738 | 7:100,348,320 | C/T | — | uncertain significance |
| rs1275330119 | 7:100,348,329 | C/T | — | uncertain significance |
| rs758826727 | 7:100,348,407 | G/A | — | uncertain significance |
| rs373196932 | 7:100,348,445 | C/T | — | likely benign |
| rs369132205 | 7:100,348,448 | G/A | — | uncertain significance |
| rs766747166 | 7:100,348,461 | G/A | — | uncertain significance |
| rs988782745 | 7:100,348,484 | G/A | — | likely benign |
| rs1370316254 | 7:100,348,815 | A/C | — | uncertain significance |
| rs780806451 | 7:100,348,833 | A/G | — | uncertain significance |
| rs747613197 | 7:100,348,836 | C/T | — | likely benign |
| rs376655494 | 7:100,349,366 | T/C | — | likely benign |
| rs369936409 | 7:100,349,367 | C/G | — | uncertain significance |
| rs1448792164 | 7:100,349,370 | G/A | — | uncertain significance |
| rs764403101 | 7:100,349,463 | G/A | — | uncertain significance |
| rs774708075 | 7:100,349,503 | C/G | — | uncertain significance |
| rs781376043 | 7:100,349,566 | A/T | — | uncertain significance |
| rs1298042262 | 7:100,349,570 | G/A | — | likely benign |
| rs200877803 | 7:100,349,634 | C/A | — | uncertain significance |
| rs13241022 | 7:100,349,687 | A/C | — | uncertain significance |
| rs756492311 | 7:100,349,710 | C/T | — | uncertain significance |
| rs527352028 | 7:100,349,775 | A/T | — | uncertain significance |
| rs2484674795 | 7:100,349,777 | C/G | — | uncertain significance |
| rs200740630 | 7:100,349,778 | A/G | — | likely benign |
| rs772161357 | 7:100,349,828 | G/A | — | likely benign |
| rs756448569 | 7:100,349,844 | T/G | — | uncertain significance |
| rs757692829 | 7:100,349,881 | C/A | — | uncertain significance |
| rs551034754 | 7:100,349,884 | T/A | — | uncertain significance |
| rs200193075 | 7:100,349,919 | T/A | — | likely benign |
| rs773842777 | 7:100,349,947 | C/A | — | uncertain significance |
| rs373427554 | 7:100,349,955 | G/A | — | uncertain significance |
| rs1192956345 | 7:100,349,961 | C/G | — | uncertain significance |
| rs781286626 | 7:100,349,982 | C/T | — | uncertain significance |
| rs1562925244 | 7:100,349,983 | C/T | — | uncertain significance |
| rs560599163 | 7:100,349,991 | T/A | — | uncertain significance |
| rs221829 | 7:100,349,994 | C/A | — | likely benign |
| rs221828 | 7:100,350,010 | C/T | — | likely benign |
| rs371312343 | 7:100,350,046 | T/C | — | likely benign |
| rs202010774 | 7:100,350,066 | C/A | — | likely benign |
| rs772020669 | 7:100,350,086 | A/G | — | likely benign |
| rs2484679869 | 7:100,350,089 | C/T | — | likely benign |
| rs189470019 | 7:100,350,159 | T/C | — | likely benign |
| rs117339995 | 7:100,350,242 | C/A | — | benign |
| rs2484681651 | 7:100,350,250 | A/G | — | uncertain significance |
| rs776514543 | 7:100,350,310 | C/A | — | uncertain significance |
| rs370504357 | 7:100,350,352 | C/T | — | uncertain significance |
| rs1808866203 | 7:100,350,548 | A/C | — | uncertain significance |
| rs199651674 | 7:100,350,582 | C/A | — | likely benign |
| rs376729135 | 7:100,350,637 | C/T | — | uncertain significance |
| rs371241253 | 7:100,350,648 | G/A | — | uncertain significance |
| rs751317677 | 7:100,350,651 | A/G | — | likely benign |
| rs1165232062 | 7:100,350,724 | C/A | — | uncertain significance |
| rs1808902820 | 7:100,350,787 | A/G | — | uncertain significance |
| rs762526583 | 7:100,350,808 | C/A | — | uncertain significance |
| rs371722808 | 7:100,352,890 | C/A | — | uncertain significance |
| rs750335987 | 7:100,352,993 | C/T | — | uncertain significance |
| rs746538636 | 7:100,353,005 | A/G | — | uncertain significance |
| rs199735231 | 7:100,355,868 | G/A | — | uncertain significance |
| rs377530896 | 7:100,355,909 | T/G | — | uncertain significance |
Showing 100 of 196 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.