rs10033762

This variant is located in the COX7B2 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

substance-related disorder

Lai D et al. “Genome-wide meta-analyses of cross substance use disorders in diverse populations.” Molecular Psychiatry 31(3):1619-1633 (2026)

Allele T

OR 7.42

p 1.0e-13

N 1,699,295

Large GWAS

multi-ancestry

About COX7B2

Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to act upstream of or within spermatogenesis. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]

View all COX7B2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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