rs10094872
This is a intron variant variant in the CASC11 gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
urinary bladder carcinoma
Rashkin SR et al. “Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts.” Nature Communications 11(1):4423 (2020)
Allele T
OR 1.23
p 3.0e-11
N 412,592
Large GWAS
European
pancreatic carcinoma
Klein AP et al. “Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.” Nature Communications 9(1):556 (2018)
Allele T
OR 1.14
p 1.0e-9
N 21,536
Meta-analysisLarge GWAS
European
Zhang M et al. “Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21.” Oncotarget 7(41):66328-66343 (2016)
Allele T
OR 1.15
p 3.0e-9
N 13,952
Large GWAS
European
cancer
Rashkin SR et al. “Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts.” Nature Communications 11(1):4423 (2020)
Allele T
OR 1.18
p 3.0e-9
N 475,312
Large GWAS
European
urinary bladder cancer
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele A
OR 0.19
p 6.0e-37
N 448,150
Major Consortium StudyLarge GWAS
European
About CASC11
Enables chromatin-protein adaptor activity and promoter-enhancer loop anchoring activity. Involved in chromatin looping and positive regulation of transcription by RNA polymerase II. Is active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all CASC11 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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