Trait
SNPs associated with Cancer risk
145 genetic variants across 54 genes have been associated with Cancer risk in published research. Key genes include AGER, AIF1, ATP8B1.
Associated variants145 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1024611 | CCL2 | Increased cancer susceptibility in Caucasian populations | Meta-analysis |
| rs2066844 | NOD2 | Increased cancer risk | Meta-analysis |
| rs1042522 | TP53 | Increased cancer susceptibility at select sites | Meta-analysis |
| rs12785878 | DHCR7 | Increased overall cancer risk | Meta-analysis |
| rs9939609 | FTO | Increased endometrial and pancreatic cancer risk | Meta-analysis |
| rs4588 | GC | Increased cancer risk in Caucasian and Asian populations | Meta-analysis |
| rs77375493 | JAK2 | GWAS association (p=8.0e-17) | Major Consortium Study |
| rs1126809 | TYR | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs10736303 | FGFR2 | GWAS association (p=8.0e-12) | Major Consortium Study |
| rs17271951 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs7895676 | FGFR2 | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs10086908 | LOC105375751 | GWAS association (p=2.0e-10) | Major Consortium Study |
| rs17632542 | KLK3 | GWAS association (p=3.0e-10) | Major Consortium Study |
| rs10993994 | MSMB | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs7130881 | LOC105369367 | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs4255548 | — | GWAS association (p=4.0e-09) | Major Consortium Study |
| rs35749174 | CHMP1A | GWAS association (p=7.0e-09) | Major Consortium Study |
| rs4242382 | — | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs245095 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs13387042 | IGFBP-AS1 | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs7500427 | TOX3 | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs10931936 | CASP8 | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs1447295 | CASC8 | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs7806086 | — | GWAS association (p=5.0e-08) | Major Consortium Study |
| rs16901949 | — | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs10505477 | CASC8 | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs4430796 | HNF1B | GWAS association (p=3.0e-09) | Major Consortium Study |
| rs1016343 | PRNCR1 | GWAS association (p=1.0e-08) | Major Consortium Study |
| rs6983267 | CASC8 | GWAS association (p=8.0e-74) | Large GWAS |
| rs12203592 | IRF4 | GWAS association (p=1.0e-49) | Large GWAS |
| rs11263763 | HNF1B | GWAS association (p=4.0e-47) | Large GWAS |
| rs111362352 | — | GWAS association (p=5.0e-33) | Large GWAS |
| rs73728618 | — | GWAS association (p=6.0e-33) | Large GWAS |
| rs12275055 | — | GWAS association (p=9.0e-33) | Large GWAS |
| rs9270747 | — | GWAS association (p=2.0e-32) | Large GWAS |
| rs7709971 | — | GWAS association (p=2.0e-31) | Large GWAS |
| rs554219 | — | GWAS association (p=4.0e-30) | Large GWAS |
| rs62516012 | CASC8 | GWAS association (p=7.0e-28) | Large GWAS |
| rs4499232 | — | GWAS association (p=2.0e-21) | Large GWAS |
| rs10941679 | — | GWAS association (p=5.0e-21) | Large GWAS |
| rs9911515 | CASC17 | GWAS association (p=1.0e-20) | Large GWAS |
| rs144898130 | CASC8 | GWAS association (p=2.0e-19) | Large GWAS |
| rs5759167 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs2349073 | FLACC1 | GWAS association (p=4.0e-18) | Large GWAS |
| rs10007915 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs11813268 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs17401449 | — | GWAS association (p=6.0e-17) | Large GWAS |
| rs34563311 | HLA-DRB1 | GWAS association (p=1.0e-16) | Large GWAS |
| rs35407 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs646157 | NEK10 | GWAS association (p=5.0e-16) | Large GWAS |
| rs9273501 | HLA-DQB1 | GWAS association (p=9.0e-16) | Large GWAS |
| rs34659644 | ZNF276 | GWAS association (p=1.0e-15) | Large GWAS |
| rs1204552 | — | GWAS association (p=7.0e-15) | Large GWAS |
| rs3016018 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs9397437 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs2763979 | HSPA1B | GWAS association (p=2.0e-14) | Large GWAS |
| rs10486567 | JAZF1 | GWAS association (p=3.0e-14) | Large GWAS |
| rs12549761 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs146836668 | — | GWAS association (p=7.0e-14) | Large GWAS |
| rs10828247 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs7717417 | — | GWAS association (p=6.0e-13) | Large GWAS |
| rs78809737 | — | GWAS association (p=8.0e-13) | Large GWAS |
| rs62237617 | TTC28 | GWAS association (p=9.0e-13) | Large GWAS |
| rs6059655 | RALY | GWAS association (p=1.0e-12) | Large GWAS |
| rs56868629 | CASC8 | GWAS association (p=1.0e-12) | Large GWAS |
| rs78378222 | TP53 | GWAS association (p=2.0e-12) | Large GWAS |
| rs4785767 | DRC4 | GWAS association (p=2.0e-12) | Large GWAS |
| rs535777 | — | GWAS association (p=4.0e-12) | Large GWAS |
| rs77282844 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs61938101 | — | GWAS association (p=5.0e-12) | Large GWAS |
| rs73169065 | MRTFA | GWAS association (p=5.0e-12) | Large GWAS |
| rs910416 | ESR1 | GWAS association (p=5.0e-12) | Large GWAS |
| rs7297051 | — | GWAS association (p=8.0e-12) | Large GWAS |
| rs2070600 | AGER | GWAS association (p=9.0e-12) | Large GWAS |
| rs6675912 | LOC124903862 | GWAS association (p=2.0e-11) | Large GWAS |
| rs45631632 | — | GWAS association (p=2.0e-11) | Large GWAS |
| rs2293607 | TERC | GWAS association (p=2.0e-11) | Large GWAS |
| rs10175462 | PAX8 | GWAS association (p=3.0e-11) | Large GWAS |
| rs130071 | CCHCR1 | GWAS association (p=3.0e-11) | Large GWAS |
| rs62073542 | — | GWAS association (p=5.0e-11) | Large GWAS |
| rs7193144 | FTO | GWAS association (p=5.0e-11) | Large GWAS |
| rs72951831 | — | GWAS association (p=7.0e-11) | Large GWAS |
| rs3769823 | CASP8 | GWAS association (p=8.0e-11) | Large GWAS |
| rs12194182 | — | GWAS association (p=1.0e-10) | Large GWAS |
| rs41263822 | HLA-DQB1 | GWAS association (p=2.0e-10) | Large GWAS |
| rs17190106 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs6801665 | — | GWAS association (p=2.0e-10) | Large GWAS |
| rs4939827 | SMAD7 | GWAS association (p=3.0e-10) | Large GWAS |
| rs1398148 | PIK3C2B | GWAS association (p=3.0e-10) | Large GWAS |
| rs114060326 | — | GWAS association (p=3.0e-10) | Large GWAS |
| rs339351 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs533143 | — | GWAS association (p=4.0e-10) | Large GWAS |
| rs150260898 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs7250689 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs6853490 | — | GWAS association (p=5.0e-10) | Large GWAS |
| rs2395191 | — | GWAS association (p=6.0e-10) | Large GWAS |
| rs34978822 | RTEL1 | GWAS association (p=8.0e-10) | Large GWAS |
| rs34451818 | AIF1 | GWAS association (p=1.0e-09) | Large GWAS |
| rs2335 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs2532389 | — | GWAS association (p=1.0e-09) | Large GWAS |
Showing the top 100 of 145 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.