DRC4

dynein regulatory complex subunit 4

Summary

This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

Known Variants293 total

rsidPosition (GRCh37)AllelesClassClinVar
rs87201016:90,088,787G/A—benign
rs224103816:90,088,904C/G—benign
rs8028791516:90,089,123T/G—benign
rs55248025416:90,089,138C/T—uncertain significance
rs254496529316:90,089,143G/C—likely benign
rs74703950216:90,089,145G/A—benign
rs11209418316:90,089,307C/T—benign
rs5849090716:90,089,313C/T—benign
rs11237242716:90,089,368C/T—likely benign
rs87085616:90,089,463C/G—benign
rs374382916:90,093,969T/C—benign
rs20055322716:90,094,024C/T—likely benign
rs203624063416:90,094,026C/G—likely benign
rs76157884216:90,094,028A/G—likely benign
rs119345394516:90,094,037A/C—likely benign
rs146470927516:90,094,057A/G—uncertain significance
rs14606655316:90,094,071A/G—uncertain significance
rs6173473216:90,094,078A/G—benign
rs215127663716:90,094,082C/T—likely benign
rs18838214716:90,094,085C/A—benign
rs131925991916:90,094,086C/G—uncertain significance
rs18534951516:90,094,094C/T—likely benign
rs76150269016:90,094,100G/A—likely benign
rs77301912616:90,094,103C/T—likely benign
rs76266471616:90,094,104G/A—uncertain significance
rs37498104516:90,094,107C/G—uncertain significance
rs20024582716:90,094,109A/G—likely benign
rs215127672016:90,094,121C/G—uncertain significance
rs56053165016:90,094,125G/A—uncertain significance
rs36899240016:90,094,141C/T—likely benign
rs76809761616:90,094,143G/A—likely benign
rs374382816:90,094,169G/A—benign
rs374382716:90,094,195A/G—benign
rs374382616:90,094,214C/T—benign
rs805544216:90,097,258G/A—benign
rs14106311216:90,097,672C/A—likely benign
rs74721984016:90,097,687G/C—likely benign
rs254346577916:90,097,690C/G—likely benign
rs76587757716:90,097,713G/T—pathogenic
rs13882903316:90,097,721C/T—likely benign
rs77505503316:90,097,725C/T—uncertain significance
rs96677776216:90,097,733G/A—likely benign
rs14266363816:90,097,739G/A—likely benign
rs254346609216:90,097,741T/C—uncertain significance
rs20021936616:90,097,747G/A—uncertain significance
rs230251316:90,097,748C/T—benign
rs78165351516:90,097,752C/T—uncertain significance
rs20139325916:90,097,753G/A—uncertain significance
rs20093956816:90,097,763A/C—likely benign
rs121850370716:90,097,769C/T—likely benign
rs55482355516:90,097,776C/G—uncertain significance
rs203655636216:90,097,791A/T—uncertain significance
rs254346648916:90,097,805G/A—pathogenic
rs36918688416:90,097,815C/T—uncertain significance
rs254346658116:90,097,820G/A—likely benign
rs77830644716:90,097,822A/G—uncertain significance
rs53560077616:90,097,833A/G—uncertain significance
rs75778984316:90,097,836A/G—uncertain significance
rs77922809616:90,097,837A/C—uncertain significance
rs14123404116:90,097,838G/T—conflicting classifications of pathogenicity
rs76814918816:90,097,848C/T—uncertain significance
rs77301894016:90,097,860C/T—uncertain significance
rs88492816:90,097,861G/A—likely benign
rs254346685716:90,097,863G/A—uncertain significance
rs13952188616:90,097,866A/C—uncertain significance
rs215128283916:90,097,874A/T—uncertain significance
rs18610071516:90,097,877C/T—likely benign
rs76434624416:90,097,878G/A—uncertain significance
rs254346706216:90,097,886G/C—uncertain significance
rs14355973216:90,097,893G/A—likely benign
rs91784298016:90,097,901C/G—uncertain significance
rs37759731216:90,097,916C/T—likely benign
rs18325324116:90,097,917G/A—likely benign
rs86837116:90,097,979A/G—benign
rs7403430616:90,098,048G/A—benign
rs435493816:90,098,828G/C—benign
rs53983077616:90,098,896C/T—likely benign
rs53319034616:90,099,034C/T—likely benign
rs432412916:90,099,061C/T—benign
rs11653705816:90,099,114A/G—benign
rs254347220116:90,099,120C/T—likely benign
rs203664954516:90,099,140A/G—likely benign
rs203665011916:90,099,150C/T—likely benign
rs14034468516:90,099,153C/G—conflicting classifications of pathogenicity
rs77001500716:90,099,155A/G—likely benign
rs254347254116:90,099,168A/C—uncertain significance
rs215128470116:90,099,173C/G—uncertain significance
rs254347266316:90,099,194G/A—likely benign
rs20101050116:90,099,224A/G—likely benign
rs55832102616:90,099,230C/T—likely benign
rs14984892116:90,099,231C/T—uncertain significance
rs14584500416:90,099,232G/A—uncertain significance
rs254347292516:90,099,242G/C—uncertain significance
rs14876041016:90,099,244G/C—benign
rs116588762516:90,099,253G/A—uncertain significance
rs37438599316:90,099,264C/T—uncertain significance
rs77110176416:90,099,303A/G—uncertain significance
rs254347326416:90,099,312G/C—uncertain significance
rs11611338516:90,099,313T/A—benign
rs102388577716:90,099,317G/C—likely benign

Showing 100 of 293 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.