rs34659644

This variant is located in the ZNF276 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cancer

Guindo-Martínez M et al. “The impact of non-additive genetic associations on age-related complex diseases.” Nature Communications 12(1):2436 (2021)

Allele A

OR 1.23

p 1.0e-15

N 56,637

Large GWAS

European

pulse pressure measurement

Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)

Allele A

OR 0.19

p 2.0e-9

N 1,028,980

Large GWAS

multi-ancestry

About ZNF276

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in kinetochore. [provided by Alliance of Genome Resources, Jul 2025]

View all ZNF276 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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