rs10111413

This is a intron variant variant in the MSC-AS1 gene.

GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

cytotoxic and regulatory T-cell molecule level

Allele A
OR 0.05
p 4.0e-14
N 47,745
Large GWAS
European

lymphocyte count

Allele A
OR 0.02
p 3.0e-13
N 394,642
Large GWAS
European
Sakaue S et al. A cross-population atlas of genetic associations for 220 human phenotypes. Nature Genetics 53(10):1415-1424 (2021)
Allele A
OR 0.02
p 2.0e-10
N 445,573
Large GWAS
multi-ancestry

lymphocyte percentage of leukocytes

Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele A
OR 0.02
p 2.0e-10
N 408,112
Large GWAS
European

systemic lupus erythematosus

Allele A
OR 0.92
p 3.0e-9
N 208,370
Meta-analysisLarge GWAS
East Asian

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…