rs10155223

This is a intron variant variant in the PALLD gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

heart shape trait

Burns R et al. “Genetic basis of right and left ventricular heart shape.” Nature Communications 15(1):9437 (2024)
Allele A
OR 0.04
p 1.0e-9
N 35,055
Large GWAS
European

About PALLD

This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

View all PALLD variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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