rs10173538

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GWAS Catalog Trait Associations (8)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

monocyte count

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.04
p 1.0e-40
N 296,975
Major Consortium StudyLarge GWAS
European

neutrophil count

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.03
p 9.0e-20
N 388,313
Major Consortium StudyLarge GWAS
multi-ancestry
Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele C
OR 0.03
p 2.0e-12
N 170,702
Large GWAS
European

hypothyroidism

White SL et al. “Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases.” Nature Genetics 58(2):307-316 (2026)
Allele T
OR 0.03
p 8.0e-17
N 2,444,128
Large GWAS
multi-ancestry

neutrophil count, basophil count

Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele T
OR 0.03
p 1.0e-12
N 170,143
Large GWAS
European

granulocyte count

Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele T
OR 0.03
p 8.0e-12
N 169,822
Large GWAS
European

leukocyte quantity

Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.02
p 9.0e-12
N 546,038
Major Consortium StudyLarge GWAS
multi-ancestry

neutrophil count, eosinophil count

Astle WJ et al. “The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.” Cell 167(5):1415-1429.e19 (2016)
Allele T
OR 0.03
p 9.0e-12
N 170,384
Large GWAS
European

birth weight

Warrington NM et al. “Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.” Nature Genetics 51(5):804-814 (2019)
Allele C
OR 0.02
p 1.0e-8
N 321,223
Large GWAS
multi-ancestry
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Research that mentions this SNP (1)

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Admixture mapping identifies African and Amerindigenous local ancestry loci associated with fetal growth
AssociationN=1,935Fasil Tekola-Ayele et al.(2021)· Human Genetics

A genome-wide admixture mapping study of 1,935 pregnant women from diverse ancestral backgrounds identified 10 African ancestry loci and 3 Amerindigenous ancestry loci associated with fetal growth measures. The lead variant rs13030825 (GALNT13) was strongly associated with longer humerus length in African Americans (β=0.44, P=6.25×10⁻⁶ at week 27; β=0.39, P=7.72×10⁻⁵ at week 40), with an FST of 0.55 between African and European populations. The findings identify ancestry-related maternal genetic loci influencing fetal growth across gestation.

Traits studied:Abdominal circumferenceBiparietal diameterBirth weightEstimated fetal weightFemur lengthFetal growth measuresHead circumferenceHumerus length
PubMedDOIMetascience Observatory

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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