rs10214237

This is a downstream gene variant variant.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

atopic eczema

Paternoster L et al. “Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.” Nature Genetics 47(12):1449-1456 (2015)

Allele T

OR 1.06

p 3.0e-14

N 116,863

Large GWAS

multi-ancestry

level of signaling threshold-regulating transmembrane adapter 1 in blood serum

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele C

OR 0.04

p 1.0e-12

N 47,745

Large GWAS

European

type 1 diabetes mellitus

Crouch DJM et al. “Bayesian Effect Size Ranking to Prioritise Genetic Risk Variants in Common Diseases for Follow-Up Studies.” Genetic Epidemiology 49(1):e22608 (2025)

Allele C

OR 0.90

p 2.0e-11

N 173,981

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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