rs10240199
This is a intron variant variant in the TMEM225B gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
cigarettes per day measurement
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele C
OR 0.02
p 2.0e-9
N 618,489
Large GWAS
European
Liu M et al. “Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.” Nature Genetics 51(2):237-244 (2019)
Allele C
OR 0.02
p 6.0e-9
N 403,928
Large GWAS
European
About TMEM225B
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM225B variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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