rs10419226
This variant is located in the CRTC1 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
esophageal adenocarcinoma, digestive system disease, Barrett's esophagus
Levine DM et al. “A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.” Nature Genetics 45(12):1487-93 (2013)
Allele A
OR 1.18
p 4.0e-10
N 7,135
Large GWAS
European
About CRTC1
Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
View all CRTC1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…