CRTC1
CREB regulated transcription coactivator 1
Summary
Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants47 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs10419226 | 19:18,803,172 | T/C | — | — |
| rs10404696 | 19:18,804,295 | G/T | — | — |
| rs4808845 | 19:18,812,024 | A/C | — | — |
| rs10423674 | 19:18,817,903 | C/G | — | — |
| rs757317 | 19:18,819,984 | C/T | intron variant | — |
| rs757318 | 19:18,820,308 | C/G | — | — |
| rs7257332 | 19:18,821,024 | T/G | — | — |
| rs34482977 | 19:18,824,038 | C/T | — | — |
| rs11881338 | 19:18,838,014 | T/C | — | — |
| rs149988248 | 19:18,839,663 | C/T | intron variant | — |
| rs146543016 | 19:18,839,683 | C/A | intron variant | — |
| rs6510997 | 19:18,847,608 | C/A | — | — |
| rs35771004 | 19:18,849,606 | G/A | — | — |
| rs117770608 | 19:18,853,737 | C/T | — | likely benign |
| rs1459932385 | 19:18,854,949 | C/T | — | uncertain significance |
| rs1471254436 | 19:18,856,710 | G/C | — | uncertain significance |
| rs1177950459 | 19:18,857,866 | G/A | — | uncertain significance |
| rs777137375 | 19:18,857,904 | C/T | — | likely benign |
| rs759854241 | 19:18,857,906 | C/T | — | uncertain significance |
| rs202136992 | 19:18,860,632 | C/T | — | uncertain significance |
| rs140269231 | 19:18,864,300 | A/G | — | benign |
| rs56300365 | 19:18,864,372 | A/G | — | uncertain significance |
| rs372512561 | 19:18,870,827 | G/A | — | likely benign |
| rs112538945 | 19:18,870,998 | G/A | — | benign |
| rs372353858 | 19:18,871,032 | G/A | — | uncertain significance |
| rs1274858564 | 19:18,876,246 | C/T | — | uncertain significance |
| rs36070283 | 19:18,876,258 | G/A | missense variant | — |
| rs1199711601 | 19:18,876,276 | A/G | — | uncertain significance |
| rs756822056 | 19:18,876,304 | C/T | — | uncertain significance |
| rs3746266 | 19:18,876,309 | A/G | missense variant | — |
| rs765726322 | 19:18,879,409 | G/A | — | uncertain significance |
| rs747932993 | 19:18,879,455 | G/A | — | uncertain significance |
| rs2512812353 | 19:18,879,460 | C/T | — | uncertain significance |
| rs2512812396 | 19:18,879,464 | C/T | — | uncertain significance |
| rs756177928 | 19:18,879,554 | C/A | — | uncertain significance |
| rs770653630 | 19:18,879,560 | C/A | — | uncertain significance |
| rs2512828282 | 19:18,885,774 | A/G | — | uncertain significance |
| rs1249639602 | 19:18,886,466 | A/G | — | uncertain significance |
| rs371799394 | 19:18,886,527 | C/T | — | uncertain significance |
| rs2512830940 | 19:18,886,532 | G/A | — | uncertain significance |
| rs754165862 | 19:18,886,551 | C/T | — | uncertain significance |
| rs144909160 | 19:18,888,027 | T/G | — | likely benign |
| rs752033260 | 19:18,888,040 | G/T | — | uncertain significance |
| rs2055011336 | 19:18,888,079 | G/A | — | uncertain significance |
| rs1415397842 | 19:18,888,121 | A/C | — | uncertain significance |
| rs762168920 | 19:18,888,154 | C/T | — | uncertain significance |
| rs10038 | 19:18,892,728 | C/A | regulatory region variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.