rs10494067

This variant is located in the NTNG1 gene.

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Research that mentions this SNP (1)

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Genetic variants associated with disordered eating
AssociationN=2,564Tracey D. Wade et al.(2013)· International Journal of Eating Disorders

This GWAS examined genetic variants associated with disordered eating in 2,564 female twins using four eating disorder phenotypes (anorexia nervosa spectrum, bulimia nervosa spectrum, purging via substances, and disordered eating behaviors). Six regions reached suggestive significance (p<5×10⁻⁷), implicating CLEC5A, LOC136242, TSHZ1, and SYTL5 for anorexia nervosa spectrum; NT5C1B for bulimia nervosa spectrum; and ATP8A2 for disordered eating behaviors. No variants reached genome-wide significance at p<10⁻⁸.

Traits studied:Anorexia nervosa spectrumBulimia nervosa spectrumDisordered eating behaviorsEating disordersPurging via substances
PubMedDOIMetascience Observatory

About NTNG1

This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015]

View all NTNG1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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