NTNG1

netrin G1

Summary

This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015]

Known Variants51 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs17505369	1:107,690,923	A/G	—	benign
rs17018473	1:107,691,096	G/C	—	benign
rs61731858	1:107,691,290	G/A	—	benign
rs75397654	1:107,691,641	T/C	—	benign
rs60650667	1:107,738,826	T/C	intron variant	—
rs145080015	1:107,826,098	A/C	intron variant	—
rs10494067	1:107,830,858	A/T	—	—
rs2525090371	1:107,866,952	C/G	—	uncertain significance
rs143347360	1:107,867,038	C/G	—	benign
rs778565104	1:107,867,057	A/G	—	uncertain significance
rs144330931	1:107,867,065	G/A	—	likely benign
rs151288291	1:107,867,087	C/T	—	benign
rs2525093771	1:107,867,239	G/C	—	uncertain significance
rs762311093	1:107,867,242	T/G	—	uncertain significance
rs143602371	1:107,867,291	A/C	—	uncertain significance
rs386352339	1:107,867,346	C/T	—	uncertain significance
rs375156633	1:107,867,452	G/T	—	uncertain significance
rs369526685	1:107,867,496	A/G	—	uncertain significance
rs146931709	1:107,867,498	T/C	—	likely benign
rs59386051	1:107,867,503	A/G	—	benign
rs142977353	1:107,867,518	G/A	—	likely benign
rs113825565	1:107,867,641	T/C	—	benign
rs1132933	1:107,867,717	C/A	—	benign
rs12035149	1:107,885,018	C/G	intron variant	—
rs11185093	1:107,886,351	G/C	intron variant	—
rs17018807	1:107,886,546	C/T	intron variant	—
rs12037004	1:107,907,401	T/A	intron variant	—
rs12754483	1:107,937,468	C/G	—	benign
rs2525597132	1:107,937,828	A/G	—	uncertain significance
rs1467384771	1:107,950,312	A/G	—	uncertain significance
rs12731224	1:107,961,159	A/G	—	benign
rs17530804	1:107,961,196	A/G	—	benign
rs1675209293	1:107,973,359	T/A	—	uncertain significance
rs201071360	1:107,973,414	A/G	—	uncertain significance
rs199902525	1:107,973,508	T/C	—	likely benign
rs1570946113	1:107,973,522	A/T	—	uncertain significance
rs2524079239	1:107,979,293	A/G	—	uncertain significance
rs1400654766	1:107,979,302	C/G	—	uncertain significance
rs911362178	1:107,979,319	G/A	—	uncertain significance
rs755713976	1:107,979,346	G/A	—	uncertain significance
rs773088683	1:107,979,380	A/T	—	uncertain significance
rs480392	1:107,979,396	A/C	—	benign
rs2524080729	1:107,979,400	T/G	—	uncertain significance
rs483206	1:107,979,679	G/T	—	benign
rs1444041	1:107,990,214	G/A	downstream gene variant	—
rs628117	1:107,997,106	C/T	intron variant	—
rs4914945	1:108,002,360	T/G	—	—
rs201741317	1:108,023,246	C/T	—	likely benign
rs201187016	1:108,023,334	G/C	—	uncertain significance
rs757348411	1:108,023,400	G/C	—	uncertain significance
rs4915045	1:108,023,589	C/A	—	benign

Gene information from NCBI Gene. Variant classifications from ClinVar.