rs1056930

This variant is located in the NRIP1 gene.

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

systolic blood pressure

Keaton JM et al. “Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.” Nature Genetics 56(5):778-791 (2024)

Allele C

OR 0.17

p 4.0e-12

N 1,028,980

Large GWAS

multi-ancestry

pulse pressure measurement

Allele C

OR 0.12

p 8.0e-12

N 1,028,980

Large GWAS

multi-ancestry

body weight

Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)

Allele T

OR 0.01

p 5.0e-8

N 928,679

Large GWAS

multi-ancestry

About NRIP1

Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein modulates transcriptional activity of the estrogen receptor. [provided by RefSeq, Jul 2008]

View all NRIP1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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