rs1078765

This variant is located in the CCSER1 gene.

GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

free cholesterol to total lipids in very large HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 6.0e-12
N 450,015
Large GWAS
multi-ancestry

total lipids in very large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 1.0e-10
N 450,015
Large GWAS
multi-ancestry

free cholesterol in HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 2.0e-10
N 450,015
Large GWAS
multi-ancestry

About CCSER1

Implicated in cocaine dependence. [provided by Alliance of Genome Resources, Apr 2025]

View all CCSER1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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